Design, statistical optimization, and characterization of Esculin-loaded transliposome nanogel for topical delivery: In-vitro, ex vivo study and dermatokinetic evaluation

Design, statistical optimization, and characterization of Esculin-loaded transliposome nanogel for topical delivery: In-vitro, ex vivo study and dermatokinetic evaluation

The purpose of this study was to prepare and optimise an Esculin-loaded transliposome (ECL-TL) for the dermal administration of ECL for skin cancer treatment. The ECL-TL formulation effectively produced closed lamellar vesicles with in-vitro drug release of 81.28 ± 2.82 % and ex-vivo penetration stu...

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Bibliographic Details
Main Author: Abdullah S. Alshetaili
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Journal of King Saud University: Science
Subjects:
Esculin
Transliposomes
Gel
Dermal
Dermatokinetic
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364724000788

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