A Rare Case of Adult Precursor B-Cell Lymphoblastic Lymphoma/Leukemia Presenting with Multiple Osteolytic Bone Lesions as Sole Manifestation
Primary precursor B-lymphoblastic lymphoma/leukemia (B-LBLL) of bone is uncommon neoplasm that accounts for less than 1% of primary bone tumors. It has been commonly reported in pediatric population but is rare in adults. We present a case of a 20-year-old man with multiple osteolytic lesions as sol...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Sciendo
2023-12-01
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| Series: | Acta Medica Bulgarica |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/amb-2023-0044 |
| _version_ | 1797387286272278528 |
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| author | Micheva I. Dimitrova S. |
| author_facet | Micheva I. Dimitrova S. |
| author_sort | Micheva I. |
| collection | DOAJ |
| description | Primary precursor B-lymphoblastic lymphoma/leukemia (B-LBLL) of bone is uncommon neoplasm that accounts for less than 1% of primary bone tumors. It has been commonly reported in pediatric population but is rare in adults. We present a case of a 20-year-old man with multiple osteolytic lesions as sole presentation of acute lymphoblastic leukemia, whose diagnosis was established by bone biopsy. A peripheral blood smear and the bone marrow aspirate showed no blast cells. The patient received treatment according to BFM 99 protocol and achieved complete response confirmed by F-FDG-PET/CT. |
| first_indexed | 2024-03-08T22:22:58Z |
| format | Article |
| id | doaj.art-d36a9d0b667e4bde8801c1dc941e75de |
| institution | Directory Open Access Journal |
| issn | 2719-5384 |
| language | English |
| last_indexed | 2024-03-08T22:22:58Z |
| publishDate | 2023-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Medica Bulgarica |
| spelling | doaj.art-d36a9d0b667e4bde8801c1dc941e75de2023-12-18T12:44:20ZengSciendoActa Medica Bulgarica2719-53842023-12-01504555810.2478/amb-2023-0044A Rare Case of Adult Precursor B-Cell Lymphoblastic Lymphoma/Leukemia Presenting with Multiple Osteolytic Bone Lesions as Sole ManifestationMicheva I.0Dimitrova S.1UMHAT “Sveta Marina”, Department of Hematology, Medical University – Varna, BulgariaUMHAT “Sveta Marina”, Department of Hematology, Medical University – Varna, BulgariaPrimary precursor B-lymphoblastic lymphoma/leukemia (B-LBLL) of bone is uncommon neoplasm that accounts for less than 1% of primary bone tumors. It has been commonly reported in pediatric population but is rare in adults. We present a case of a 20-year-old man with multiple osteolytic lesions as sole presentation of acute lymphoblastic leukemia, whose diagnosis was established by bone biopsy. A peripheral blood smear and the bone marrow aspirate showed no blast cells. The patient received treatment according to BFM 99 protocol and achieved complete response confirmed by F-FDG-PET/CT.https://doi.org/10.2478/amb-2023-0044acute lymphoblastic lymphoma/leukemiabone lesionspet/ct |
| spellingShingle | Micheva I. Dimitrova S. A Rare Case of Adult Precursor B-Cell Lymphoblastic Lymphoma/Leukemia Presenting with Multiple Osteolytic Bone Lesions as Sole Manifestation Acta Medica Bulgarica acute lymphoblastic lymphoma/leukemia bone lesions pet/ct |
| title | A Rare Case of Adult Precursor B-Cell Lymphoblastic Lymphoma/Leukemia Presenting with Multiple Osteolytic Bone Lesions as Sole Manifestation |
| title_full | A Rare Case of Adult Precursor B-Cell Lymphoblastic Lymphoma/Leukemia Presenting with Multiple Osteolytic Bone Lesions as Sole Manifestation |
| title_fullStr | A Rare Case of Adult Precursor B-Cell Lymphoblastic Lymphoma/Leukemia Presenting with Multiple Osteolytic Bone Lesions as Sole Manifestation |
| title_full_unstemmed | A Rare Case of Adult Precursor B-Cell Lymphoblastic Lymphoma/Leukemia Presenting with Multiple Osteolytic Bone Lesions as Sole Manifestation |
| title_short | A Rare Case of Adult Precursor B-Cell Lymphoblastic Lymphoma/Leukemia Presenting with Multiple Osteolytic Bone Lesions as Sole Manifestation |
| title_sort | rare case of adult precursor b cell lymphoblastic lymphoma leukemia presenting with multiple osteolytic bone lesions as sole manifestation |
| topic | acute lymphoblastic lymphoma/leukemia bone lesions pet/ct |
| url | https://doi.org/10.2478/amb-2023-0044 |
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