Inflammatory responses involved in post-cardiac arrest brain injury: mechanisms, regulation, and therapeutic potential

Inflammatory responses involved in post-cardiac arrest brain injury: mechanisms, regulation, and therapeutic potential

Neuroinflammation plays a key role in the pathogenesis of post-cardiac arrest (CA) brain injury. Innate immune cells sense a variety of danger signals through pattern-recognition receptors and evoke rapidly after ischemic challenge, triggering inflammatory responses and amplifying brain damage. A pr...

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Bibliographic Details
Main Authors: Yuzhen Zhang, Zhentong Li, Kunxue Zhang, Yuan Chang, Jiancong Chen, Murad Al-Nusaif, Suyue Pan, Kaibin Huang
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2023-04-01
Series:Exploration of Neuroscience
Subjects:
cardiac arrest
neuroinflammation
innate immune recognition
programmed cell death
microglia
Online Access:https://www.explorationpub.com/Journals/en/Article/100614

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