Steerable-filter based quantification of axonal populations at the developing optic chiasm reveal significant defects in <it>Slit2</it><sup><it>−/−</it></sup> as well as <it>Slit1</it><sup><it>−/−</it></sup><it>Slit2</it><sup><it>−/−</it></sup> embryos

Steerable-filter based quantification of axonal populations at the developing optic chiasm reveal significant defects in <it>Slit2</it><sup><it>−/−</it></sup> as well as <it>Slit1</it><sup><it>−/−</it></sup><it>Slit2</it><sup><it>−/−</it></sup> embryos

<p>Abstract</p> <p>Background</p> <p>Previous studies have suggested that the axon guidance proteins Slit1 and Slit2 co-operate to establish the optic chiasm in its correct position at the ventral diencephalic midline. This is based on the observation that, although bot...

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Bibliographic Details
Main Authors: Down Matthew, Willshaw David A, Pratt Thomas, Price David J
Format: Article
Language:English
Published: BMC 2013-01-01
Series:BMC Neuroscience
Subjects:
Axon guidance
Optic chiasm
Retinal axon
Slit
Steerable filter
Online Access:http://www.biomedcentral.com/1471-2202/14/9

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