Perturbação psicótica aguda associada à vigabatrina.
Vigabatrin, a drug mainly used in the treatment of therapy-resistant epilepsy, has been associated to a large range of adverse effects, including acute psychotic disorders. The authors report the case of a 44-year-old patient with drug-resistant temporal lobe epilepsy that developed an acute psychot...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Ordem dos Médicos
2000-06-01
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| Series: | Acta Médica Portuguesa |
| Online Access: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1772 |
| _version_ | 1811242457999867904 |
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| author | M Xavier M S Bento D P Pereira J M De Almeida |
| author_facet | M Xavier M S Bento D P Pereira J M De Almeida |
| author_sort | M Xavier |
| collection | DOAJ |
| description | Vigabatrin, a drug mainly used in the treatment of therapy-resistant epilepsy, has been associated to a large range of adverse effects, including acute psychotic disorders. The authors report the case of a 44-year-old patient with drug-resistant temporal lobe epilepsy that developed an acute psychotic episode about three weeks after initiating medication with vigabatrin. After the withdrawal of vigabatrin and the addition of an antipsychotic drug, the clinical picture improved promptly and the patient was discharged within a short period of time. The authors discuss the patient's diagnosis, the possible mechanisms of vigabatrin-associated psychosis and the therapeutic approach, stressing the questions that concern vigabatrin prescription and withdrawal. |
| first_indexed | 2024-04-12T13:51:33Z |
| format | Article |
| id | doaj.art-d36dc1e1e7c84f3b9f440c01fecc32e3 |
| institution | Directory Open Access Journal |
| issn | 0870-399X 1646-0758 |
| language | English |
| last_indexed | 2024-04-12T13:51:33Z |
| publishDate | 2000-06-01 |
| publisher | Ordem dos Médicos |
| record_format | Article |
| series | Acta Médica Portuguesa |
| spelling | doaj.art-d36dc1e1e7c84f3b9f440c01fecc32e32022-12-22T03:30:30ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07582000-06-0113310.20344/amp.1772Perturbação psicótica aguda associada à vigabatrina.M Xavier0M S BentoD P PereiraJ M De AlmeidaClínica Universitária da Faculdade de Ciências Médicas de Lisboa.Vigabatrin, a drug mainly used in the treatment of therapy-resistant epilepsy, has been associated to a large range of adverse effects, including acute psychotic disorders. The authors report the case of a 44-year-old patient with drug-resistant temporal lobe epilepsy that developed an acute psychotic episode about three weeks after initiating medication with vigabatrin. After the withdrawal of vigabatrin and the addition of an antipsychotic drug, the clinical picture improved promptly and the patient was discharged within a short period of time. The authors discuss the patient's diagnosis, the possible mechanisms of vigabatrin-associated psychosis and the therapeutic approach, stressing the questions that concern vigabatrin prescription and withdrawal.https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1772 |
| spellingShingle | M Xavier M S Bento D P Pereira J M De Almeida Perturbação psicótica aguda associada à vigabatrina. Acta Médica Portuguesa |
| title | Perturbação psicótica aguda associada à vigabatrina. |
| title_full | Perturbação psicótica aguda associada à vigabatrina. |
| title_fullStr | Perturbação psicótica aguda associada à vigabatrina. |
| title_full_unstemmed | Perturbação psicótica aguda associada à vigabatrina. |
| title_short | Perturbação psicótica aguda associada à vigabatrina. |
| title_sort | perturbacao psicotica aguda associada a vigabatrina |
| url | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1772 |
| work_keys_str_mv | AT mxavier perturbacaopsicoticaagudaassociadaavigabatrina AT msbento perturbacaopsicoticaagudaassociadaavigabatrina AT dppereira perturbacaopsicoticaagudaassociadaavigabatrina AT jmdealmeida perturbacaopsicoticaagudaassociadaavigabatrina |