Whole transcriptome RNA-Seq analysis of breast cancer recurrence risk using formalin-fixed paraffin-embedded tumor tissue.

Whole transcriptome RNA-Seq analysis of breast cancer recurrence risk using formalin-fixed paraffin-embedded tumor tissue.

RNA biomarkers discovered by RT-PCR-based gene expression profiling of archival formalin-fixed paraffin-embedded (FFPE) tissue form the basis for widely used clinical diagnostic tests; however, RT-PCR is practically constrained in the number of transcripts that can be interrogated. We have developed...

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Main Authors: Dominick Sinicropi, Kunbin Qu, Francois Collin, Michael Crager, Mei-Lan Liu, Robert J Pelham, Mylan Pho, Andrew Dei Rossi, Jennie Jeong, Aaron Scott, Ranjana Ambannavar, Christina Zheng, Raul Mena, Jose Esteban, James Stephans, John Morlan, Joffre Baker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3396611?pdf=render

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