Epitopes in the capsular polysaccharide and the porin OmpK36 receptors are required for bacteriophage infection of Klebsiella pneumoniae

Epitopes in the capsular polysaccharide and the porin OmpK36 receptors are required for bacteriophage infection of Klebsiella pneumoniae

Summary: To kill bacteria, bacteriophages (phages) must first bind to a receptor, triggering the release of the phage DNA into the bacterial cell. Many bacteria secrete polysaccharides that had been thought to shield bacterial cells from phage attack. We use a comprehensive genetic screen to disting...

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Bibliographic Details
Main Authors: Rhys A. Dunstan, Rebecca S. Bamert, Kher Shing Tan, Uvini Imbulgoda, Christopher K. Barlow, George Taiaroa, Derek J. Pickard, Ralf B. Schittenhelm, Gordon Dougan, Francesca L. Short, Trevor Lithgow
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Cell Reports
Subjects:
CP: Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723005624

Internet

http://www.sciencedirect.com/science/article/pii/S2211124723005624

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