Small renal masses in kidney transplantation: Overview of clinical impact and management in donors and recipients
Kidney transplantation is the best replacement treatment for the end-stage renal disease. Currently, the imbalance between the number of patients on a transplant list and the number of organs available constitutes the crucial limitation of this approach. To expand the pool of organs amenable for tra...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-07-01
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| Series: | Asian Journal of Urology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221438822200039X |
| _version_ | 1811216469134934016 |
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| author | Alberto Piana Iulia Andras Pietro Diana Paolo Verri Andrea Gallioli Riccardo Campi Thomas Prudhomme Vital Hevia Romain Boissier Alberto Breda Angelo Territo |
| author_facet | Alberto Piana Iulia Andras Pietro Diana Paolo Verri Andrea Gallioli Riccardo Campi Thomas Prudhomme Vital Hevia Romain Boissier Alberto Breda Angelo Territo |
| author_sort | Alberto Piana |
| collection | DOAJ |
| description | Kidney transplantation is the best replacement treatment for the end-stage renal disease. Currently, the imbalance between the number of patients on a transplant list and the number of organs available constitutes the crucial limitation of this approach. To expand the pool of organs amenable for transplantation, kidneys coming from older patients have been employed; however, the combination of these organs in conjunction with the chronic use of immunosuppressive therapy increases the risk of incidence of graft small renal tumors. This narrative review aims to provide the state of the art on the clinical impact and management of incidentally diagnosed small renal tumors in either donors or recipients. According to the most updated evidence, the use of grafts with a small renal mass, after bench table tumor excision, may be considered a safe option for high-risk patients in hemodialysis. On the other hand, an early small renal mass finding on periodic ultrasound-evaluation in the graft should allow to perform a conservative treatment in order to preserve renal function. Finally, in case of a renal tumor in native kidney, a radical nephrectomy is usually recommended. |
| first_indexed | 2024-04-12T06:39:36Z |
| format | Article |
| id | doaj.art-d36f369be0664046927bfe2df314a249 |
| institution | Directory Open Access Journal |
| issn | 2214-3882 |
| language | English |
| last_indexed | 2024-04-12T06:39:36Z |
| publishDate | 2022-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Asian Journal of Urology |
| spelling | doaj.art-d36f369be0664046927bfe2df314a2492022-12-22T03:43:45ZengElsevierAsian Journal of Urology2214-38822022-07-0193208214Small renal masses in kidney transplantation: Overview of clinical impact and management in donors and recipientsAlberto Piana0Iulia Andras1Pietro Diana2Paolo Verri3Andrea Gallioli4Riccardo Campi5Thomas Prudhomme6Vital Hevia7Romain Boissier8Alberto Breda9Angelo Territo10Department of Urology, Fundació Puigvert, Autonoma University of Barcelona, Spain; Department of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Turin, Italy; Corresponding author. Department of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Turin, Italy.Urology Department, Iuliu Hatieganu University of Medicine and Pharmacy and Municipal Hospital, Cluj-Napoca, RomaniaDepartment of Urology, Fundació Puigvert, Autonoma University of Barcelona, SpainDepartment of Urology, Fundació Puigvert, Autonoma University of Barcelona, Spain; Department of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Turin, ItalyDepartment of Urology, Fundació Puigvert, Autonoma University of Barcelona, SpainUnit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy; Department of Experimental and Clinical Medicine, University of Florence, Florence, ItalyDepartment of Urology and Kidney Transplantation, Toulouse University Hospital, Toulouse, FranceHospital Universitario Ramon y Cajal. Alcala University, Instituto Ramon y Cajal de Investigación Sanitaria (IRYCIS), Madrid, SpainAix-Marseille université, service de chirurgie urologique et de transplantation rénale, CHU Conception, AP-HM, Marseille, FranceDepartment of Urology, Fundació Puigvert, Autonoma University of Barcelona, SpainDepartment of Urology, Fundació Puigvert, Autonoma University of Barcelona, SpainKidney transplantation is the best replacement treatment for the end-stage renal disease. Currently, the imbalance between the number of patients on a transplant list and the number of organs available constitutes the crucial limitation of this approach. To expand the pool of organs amenable for transplantation, kidneys coming from older patients have been employed; however, the combination of these organs in conjunction with the chronic use of immunosuppressive therapy increases the risk of incidence of graft small renal tumors. This narrative review aims to provide the state of the art on the clinical impact and management of incidentally diagnosed small renal tumors in either donors or recipients. According to the most updated evidence, the use of grafts with a small renal mass, after bench table tumor excision, may be considered a safe option for high-risk patients in hemodialysis. On the other hand, an early small renal mass finding on periodic ultrasound-evaluation in the graft should allow to perform a conservative treatment in order to preserve renal function. Finally, in case of a renal tumor in native kidney, a radical nephrectomy is usually recommended.http://www.sciencedirect.com/science/article/pii/S221438822200039XSmall renal massRenal cancerKidney transplantationNephron-sparing treatment |
| spellingShingle | Alberto Piana Iulia Andras Pietro Diana Paolo Verri Andrea Gallioli Riccardo Campi Thomas Prudhomme Vital Hevia Romain Boissier Alberto Breda Angelo Territo Small renal masses in kidney transplantation: Overview of clinical impact and management in donors and recipients Asian Journal of Urology Small renal mass Renal cancer Kidney transplantation Nephron-sparing treatment |
| title | Small renal masses in kidney transplantation: Overview of clinical impact and management in donors and recipients |
| title_full | Small renal masses in kidney transplantation: Overview of clinical impact and management in donors and recipients |
| title_fullStr | Small renal masses in kidney transplantation: Overview of clinical impact and management in donors and recipients |
| title_full_unstemmed | Small renal masses in kidney transplantation: Overview of clinical impact and management in donors and recipients |
| title_short | Small renal masses in kidney transplantation: Overview of clinical impact and management in donors and recipients |
| title_sort | small renal masses in kidney transplantation overview of clinical impact and management in donors and recipients |
| topic | Small renal mass Renal cancer Kidney transplantation Nephron-sparing treatment |
| url | http://www.sciencedirect.com/science/article/pii/S221438822200039X |
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