Generation of an NCS1 gene knockout human induced pluripotent stem cell line using CRISPR/Cas9

NCS1 (Neuronal calcium sensor protein 1) encodes a highly conserved calcium binding protein abundantly expressed in neurons. It modulates intracellular calcium homeostasis, calcium-dependent signaling pathways as well as neuronal transmission and plasticity. Here, we generated a NCS1 knockout human...

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Bibliographic Details
Main Authors: Smilla K. Maierhof, Christian Schinke, Janine Cernoch, Lois Hew, Laura Pauline Bruske, Valeria Fernandez Vallone, Kristin Fischer, Harald Stachelscheid, Petra Huehnchen, Matthias Endres, Sebastian Diecke, Narasimha Swamy Telugu, Wolfgang Boehmerle
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506123002398