Viscoelastic modulus of agarose gels by magnetic resonance elastography using Micro-MRI
This study aimed to apply magnetic resonance elastography (MRE) using micro-magnetic resonance imaging (micro-MRI) system for the measurements of viscoelastic modulus in soft matters. The rectangular specimens of 90 × 70 × 50 mm were made of agarose gel with five kinds of stiffness by changing conce...
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| Format: | Article |
| Language: | English |
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The Japan Society of Mechanical Engineers
2015-04-01
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| Series: | Mechanical Engineering Journal |
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| Online Access: | https://www.jstage.jst.go.jp/article/mej/2/3/2_14-00417/_pdf/-char/en |
| _version_ | 1818429806349385728 |
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| author | Hayato SUZUKI Shigeru TADANO Mototeru GOTO Satoshi YAMADA Kazuhiro FUJISAKI Itsuro KAJIWARA Mikio SUGA Gen NAKAMURA |
| author_facet | Hayato SUZUKI Shigeru TADANO Mototeru GOTO Satoshi YAMADA Kazuhiro FUJISAKI Itsuro KAJIWARA Mikio SUGA Gen NAKAMURA |
| author_sort | Hayato SUZUKI |
| collection | DOAJ |
| description | This study aimed to apply magnetic resonance elastography (MRE) using micro-magnetic resonance imaging (micro-MRI) system for the measurements of viscoelastic modulus in soft matters. The rectangular specimens of 90 × 70 × 50 mm were made of agarose gel with five kinds of stiffness by changing concentrations. The specimens were oscillated with longitudinal waves transmitted by an elastic-bar from a vibration generator in a micro-MRI system. Since the viscoelastic properties depend on the excitation frequency and amplitude, the experimental conditions were selected in the range of 50-250 Hz and 0.1-0.5 mm. The viscoelastic modulus was expressed as storage shear modulus G´ and loss shear modulus G˝. As a result, G´ increased with the frequency and amplitude, and the difference of G´ between hard and soft gels was obtained. The viscoelastic modulus of agarose gels was measured using the MRE system under the excitation conditions. Furthermore, double-layer specimens composed of 0.6 and 2.0 wt% gels were examined as an application of the MRE system. The difference of wave pattern between the hard and soft parts was observed. The values of G´ in the soft parts of the double-layer specimens corresponded to the value of the single-layer specimen, but the values of G´ in the hard parts were varied. |
| first_indexed | 2024-12-14T15:23:22Z |
| format | Article |
| id | doaj.art-d37449c5947046ae978e5dd975c717e1 |
| institution | Directory Open Access Journal |
| issn | 2187-9745 |
| language | English |
| last_indexed | 2024-12-14T15:23:22Z |
| publishDate | 2015-04-01 |
| publisher | The Japan Society of Mechanical Engineers |
| record_format | Article |
| series | Mechanical Engineering Journal |
| spelling | doaj.art-d37449c5947046ae978e5dd975c717e12022-12-21T22:56:04ZengThe Japan Society of Mechanical EngineersMechanical Engineering Journal2187-97452015-04-012314-0041714-0041710.1299/mej.14-00417mejViscoelastic modulus of agarose gels by magnetic resonance elastography using Micro-MRIHayato SUZUKI0Shigeru TADANO1Mototeru GOTO2Satoshi YAMADA3Kazuhiro FUJISAKI4Itsuro KAJIWARA5Mikio SUGA6Gen NAKAMURA7Division of Human Mechanical Systems and Design, Graduate School of Engineering, Hokkaido UniversityDivision of Human Mechanical Systems and Design, Faculty of Engineering, Hokkaido UniversityDivision of Human Mechanical Systems and Design, Graduate School of Engineering, Hokkaido UniversityDivision of Human Mechanical Systems and Design, Faculty of Engineering, Hokkaido UniversityDepartment of Intelligent Machines and System Engineering, Faculty of Science and TechnologyDivision of Human Mechanical Systems and Design, Faculty of Engineering, Hokkaido UniversityDepartment of Medical System Engineering, Division of Artificial Systems Science, Graduate School of Engineering, Chiba UniversityDepartment of Mathematics, Faculty of Science, Hokkaido UniversityThis study aimed to apply magnetic resonance elastography (MRE) using micro-magnetic resonance imaging (micro-MRI) system for the measurements of viscoelastic modulus in soft matters. The rectangular specimens of 90 × 70 × 50 mm were made of agarose gel with five kinds of stiffness by changing concentrations. The specimens were oscillated with longitudinal waves transmitted by an elastic-bar from a vibration generator in a micro-MRI system. Since the viscoelastic properties depend on the excitation frequency and amplitude, the experimental conditions were selected in the range of 50-250 Hz and 0.1-0.5 mm. The viscoelastic modulus was expressed as storage shear modulus G´ and loss shear modulus G˝. As a result, G´ increased with the frequency and amplitude, and the difference of G´ between hard and soft gels was obtained. The viscoelastic modulus of agarose gels was measured using the MRE system under the excitation conditions. Furthermore, double-layer specimens composed of 0.6 and 2.0 wt% gels were examined as an application of the MRE system. The difference of wave pattern between the hard and soft parts was observed. The values of G´ in the soft parts of the double-layer specimens corresponded to the value of the single-layer specimen, but the values of G´ in the hard parts were varied.https://www.jstage.jst.go.jp/article/mej/2/3/2_14-00417/_pdf/-char/enmagnetic resonance elastographymagnetic resonance imagingviscoelasticitysoft matter stiffnesselastic modulus |
| spellingShingle | Hayato SUZUKI Shigeru TADANO Mototeru GOTO Satoshi YAMADA Kazuhiro FUJISAKI Itsuro KAJIWARA Mikio SUGA Gen NAKAMURA Viscoelastic modulus of agarose gels by magnetic resonance elastography using Micro-MRI Mechanical Engineering Journal magnetic resonance elastography magnetic resonance imaging viscoelasticity soft matter stiffness elastic modulus |
| title | Viscoelastic modulus of agarose gels by magnetic resonance elastography using Micro-MRI |
| title_full | Viscoelastic modulus of agarose gels by magnetic resonance elastography using Micro-MRI |
| title_fullStr | Viscoelastic modulus of agarose gels by magnetic resonance elastography using Micro-MRI |
| title_full_unstemmed | Viscoelastic modulus of agarose gels by magnetic resonance elastography using Micro-MRI |
| title_short | Viscoelastic modulus of agarose gels by magnetic resonance elastography using Micro-MRI |
| title_sort | viscoelastic modulus of agarose gels by magnetic resonance elastography using micro mri |
| topic | magnetic resonance elastography magnetic resonance imaging viscoelasticity soft matter stiffness elastic modulus |
| url | https://www.jstage.jst.go.jp/article/mej/2/3/2_14-00417/_pdf/-char/en |
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