The Role of Autotaxin and LPA Signaling in Embryonic Development, Pathophysiology and Cancer
Autotaxin (ATX) or Ectonucleotide Pyrophosphatase/Phosphodiesterase 2 (ENPP2) is a secreted enzyme with lysophospholipase D activity, with its primary function being the extracellular hydrolysis of lysophosphatidylcholine (LPC) to lysophosphatidic acid (LPA), a bioactive lipid [...]
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/9/8325 |
| _version_ | 1797602403306962944 |
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| author | Christiana Magkrioti Eleanna Kaffe Vassilis Aidinis |
| author_facet | Christiana Magkrioti Eleanna Kaffe Vassilis Aidinis |
| author_sort | Christiana Magkrioti |
| collection | DOAJ |
| description | Autotaxin (ATX) or Ectonucleotide Pyrophosphatase/Phosphodiesterase 2 (ENPP2) is a secreted enzyme with lysophospholipase D activity, with its primary function being the extracellular hydrolysis of lysophosphatidylcholine (LPC) to lysophosphatidic acid (LPA), a bioactive lipid [...] |
| first_indexed | 2024-03-11T04:16:34Z |
| format | Article |
| id | doaj.art-d375dd65efc3482789228e48a0e6b6e6 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T04:16:34Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-d375dd65efc3482789228e48a0e6b6e62023-11-17T23:08:04ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-05-01249832510.3390/ijms24098325The Role of Autotaxin and LPA Signaling in Embryonic Development, Pathophysiology and CancerChristiana Magkrioti0Eleanna Kaffe1Vassilis Aidinis2Institute for Fundamental Biomedical Research, Biomedical Sciences Research Center Alexander Fleming, 16672 Athens, GreeceInstitute for Fundamental Biomedical Research, Biomedical Sciences Research Center Alexander Fleming, 16672 Athens, GreeceInstitute for Fundamental Biomedical Research, Biomedical Sciences Research Center Alexander Fleming, 16672 Athens, GreeceAutotaxin (ATX) or Ectonucleotide Pyrophosphatase/Phosphodiesterase 2 (ENPP2) is a secreted enzyme with lysophospholipase D activity, with its primary function being the extracellular hydrolysis of lysophosphatidylcholine (LPC) to lysophosphatidic acid (LPA), a bioactive lipid [...]https://www.mdpi.com/1422-0067/24/9/8325n/a |
| spellingShingle | Christiana Magkrioti Eleanna Kaffe Vassilis Aidinis The Role of Autotaxin and LPA Signaling in Embryonic Development, Pathophysiology and Cancer International Journal of Molecular Sciences n/a |
| title | The Role of Autotaxin and LPA Signaling in Embryonic Development, Pathophysiology and Cancer |
| title_full | The Role of Autotaxin and LPA Signaling in Embryonic Development, Pathophysiology and Cancer |
| title_fullStr | The Role of Autotaxin and LPA Signaling in Embryonic Development, Pathophysiology and Cancer |
| title_full_unstemmed | The Role of Autotaxin and LPA Signaling in Embryonic Development, Pathophysiology and Cancer |
| title_short | The Role of Autotaxin and LPA Signaling in Embryonic Development, Pathophysiology and Cancer |
| title_sort | role of autotaxin and lpa signaling in embryonic development pathophysiology and cancer |
| topic | n/a |
| url | https://www.mdpi.com/1422-0067/24/9/8325 |
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