Guideline for design of substrate stiffness for mesenchymal stem cell culture based on heterogeneity of YAP and RUNX2 responses

Mesenchymal stem cells (MSCs) have the potential for self-renewal and multipotency to differentiate into various lineages. Thus, they are of great interest in regenerative medicine as a cell source for tissue engineering. Substrate stiffness is one of the most extensively studied exogenous physical...

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Bibliographic Details
Main Authors: Hiromi Miyoshi, Masashi Yamazaki, Hiromichi Fujie, Satoru Kidoaki
Format: Article
Language:English
Published: The Biophysical Society of Japan 2023-05-01
Series:Biophysics and Physicobiology
Subjects:
Online Access:https://doi.org/10.2142/biophysico.bppb-v20.0018