Efficacy of valdoxan in the prevention and treatment of post-stroke depression
The efficacy of valdoxan (agomelatine) used to prevent and treat post-stroke depression was analyzed. The study enrolled 49 patients (21 men and 28 women; mean age 61+5.5years) in the acute period of ischemic stroke in different vascular basins (a study group). A control group included 50 patients (...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IMA-PRESS LLC
2012-09-01
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| Series: | Неврология, нейропсихиатрия, психосоматика |
| Subjects: | |
| Online Access: | https://nnp.ima-press.net/nnp/article/view/143 |
| _version_ | 1827062940305457152 |
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| author | Dina Rustemovna Khasanova Yu V Zhitkova A A Safiullina |
| author_facet | Dina Rustemovna Khasanova Yu V Zhitkova A A Safiullina |
| author_sort | Dina Rustemovna Khasanova |
| collection | DOAJ |
| description | The efficacy of valdoxan (agomelatine) used to prevent and treat post-stroke depression was analyzed. The study enrolled 49 patients (21 men and 28 women; mean age 61+5.5years) in the acute period of ischemic stroke in different vascular basins (a study group). A control group included 50 patients (24 men and 26 women; mean age 64+4.8 years) who were comparable with the study group of patients and who did not receive valdoxan. The duration of a follow-up was 6 months. During valdoxan therapy, there were better changes in recovery with a rapider regression of neurological disorders in patients with moderate stroke as compared with the control group (according to the National Institute of Health Stroke Scale (NIHSS). The administration of valdoxan prevents depression, sleep disorders, pain syndromes, and cognitive impairments in the acute and early rehabilitation period of stroke. |
| first_indexed | 2024-04-10T02:04:38Z |
| format | Article |
| id | doaj.art-d379f886cb624c5cb3fcd961bccfcde3 |
| institution | Directory Open Access Journal |
| issn | 2074-2711 2310-1342 |
| language | Russian |
| last_indexed | 2025-02-18T20:04:42Z |
| publishDate | 2012-09-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Неврология, нейропсихиатрия, психосоматика |
| spelling | doaj.art-d379f886cb624c5cb3fcd961bccfcde32024-10-17T16:15:20ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422012-09-0143485310.14412/2074-2711-2012-403143Efficacy of valdoxan in the prevention and treatment of post-stroke depressionDina Rustemovna KhasanovaYu V ZhitkovaA A SafiullinaThe efficacy of valdoxan (agomelatine) used to prevent and treat post-stroke depression was analyzed. The study enrolled 49 patients (21 men and 28 women; mean age 61+5.5years) in the acute period of ischemic stroke in different vascular basins (a study group). A control group included 50 patients (24 men and 26 women; mean age 64+4.8 years) who were comparable with the study group of patients and who did not receive valdoxan. The duration of a follow-up was 6 months. During valdoxan therapy, there were better changes in recovery with a rapider regression of neurological disorders in patients with moderate stroke as compared with the control group (according to the National Institute of Health Stroke Scale (NIHSS). The administration of valdoxan prevents depression, sleep disorders, pain syndromes, and cognitive impairments in the acute and early rehabilitation period of stroke.https://nnp.ima-press.net/nnp/article/view/143strokepost-stroke depressionvaldoxancognitive impairments |
| spellingShingle | Dina Rustemovna Khasanova Yu V Zhitkova A A Safiullina Efficacy of valdoxan in the prevention and treatment of post-stroke depression Неврология, нейропсихиатрия, психосоматика stroke post-stroke depression valdoxan cognitive impairments |
| title | Efficacy of valdoxan in the prevention and treatment of post-stroke depression |
| title_full | Efficacy of valdoxan in the prevention and treatment of post-stroke depression |
| title_fullStr | Efficacy of valdoxan in the prevention and treatment of post-stroke depression |
| title_full_unstemmed | Efficacy of valdoxan in the prevention and treatment of post-stroke depression |
| title_short | Efficacy of valdoxan in the prevention and treatment of post-stroke depression |
| title_sort | efficacy of valdoxan in the prevention and treatment of post stroke depression |
| topic | stroke post-stroke depression valdoxan cognitive impairments |
| url | https://nnp.ima-press.net/nnp/article/view/143 |
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