New Constituents from the Korean Sponge Plakortis simplex

Six new cyclic peroxides (1–6) were isolated from the Korean sponge Plakortis simplex, along with two new alkylpyridinium alkaloids (7 and 8). The structures of these compounds were completely determined by a combination of NMR analysis and chemical reactions. Compounds 1–6 exhibited cytotoxic/antif...

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Main Authors: Ok-Hwa Kang, Buyng Su Hwang, Jung-Rae Rho, Dong-Yeul Kwon, Jung Soon Oh
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/11/11/4407
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author Ok-Hwa Kang
Buyng Su Hwang
Jung-Rae Rho
Dong-Yeul Kwon
Jung Soon Oh
author_facet Ok-Hwa Kang
Buyng Su Hwang
Jung-Rae Rho
Dong-Yeul Kwon
Jung Soon Oh
author_sort Ok-Hwa Kang
collection DOAJ
description Six new cyclic peroxides (1–6) were isolated from the Korean sponge Plakortis simplex, along with two new alkylpyridinium alkaloids (7 and 8). The structures of these compounds were completely determined by a combination of NMR analysis and chemical reactions. Compounds 1–6 exhibited cytotoxic/antifungal activities against RAW264.7 cells and Candida albicans.
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spelling doaj.art-d37eeb968abe490d91ec5148aff888bd2022-12-22T04:03:49ZengMDPI AGMarine Drugs1660-33972013-11-0111114407441810.3390/md11114407New Constituents from the Korean Sponge Plakortis simplexOk-Hwa KangBuyng Su HwangJung-Rae RhoDong-Yeul KwonJung Soon OhSix new cyclic peroxides (1–6) were isolated from the Korean sponge Plakortis simplex, along with two new alkylpyridinium alkaloids (7 and 8). The structures of these compounds were completely determined by a combination of NMR analysis and chemical reactions. Compounds 1–6 exhibited cytotoxic/antifungal activities against RAW264.7 cells and Candida albicans.http://www.mdpi.com/1660-3397/11/11/4407Plakortis simplexcyclic peroxidecyclic peroxyketalpyridiniumNMR
spellingShingle Ok-Hwa Kang
Buyng Su Hwang
Jung-Rae Rho
Dong-Yeul Kwon
Jung Soon Oh
New Constituents from the Korean Sponge Plakortis simplex
Marine Drugs
Plakortis simplex
cyclic peroxide
cyclic peroxyketal
pyridinium
NMR
title New Constituents from the Korean Sponge Plakortis simplex
title_full New Constituents from the Korean Sponge Plakortis simplex
title_fullStr New Constituents from the Korean Sponge Plakortis simplex
title_full_unstemmed New Constituents from the Korean Sponge Plakortis simplex
title_short New Constituents from the Korean Sponge Plakortis simplex
title_sort new constituents from the korean sponge plakortis simplex
topic Plakortis simplex
cyclic peroxide
cyclic peroxyketal
pyridinium
NMR
url http://www.mdpi.com/1660-3397/11/11/4407
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