Comparison of Survival Outcomes between Minimally Invasive Surgery and Open Radical Hysterectomy in Early-Stage Cervical Cancer
Objectives: To compare the survival outcomes between minimally invasive surgery (MIS) and laparotomy radical hysterectomy in patients with early-stage cervical cancer. Methods: We conducted a retrospective study involving women who received a radical hysterectomy for cervical cancer, stage IA1 with...
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| Format: | Article |
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MDPI AG
2022-04-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/14/9/2117 |
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| author | I.-Ning Chen I.-Te Wang Hsueh-Yu Mu J.-Timothy Qiu Wei-Min Liu Ching-Wen Chang Yen-Hsieh Chiu |
| author_facet | I.-Ning Chen I.-Te Wang Hsueh-Yu Mu J.-Timothy Qiu Wei-Min Liu Ching-Wen Chang Yen-Hsieh Chiu |
| author_sort | I.-Ning Chen |
| collection | DOAJ |
| description | Objectives: To compare the survival outcomes between minimally invasive surgery (MIS) and laparotomy radical hysterectomy in patients with early-stage cervical cancer. Methods: We conducted a retrospective study involving women who received a radical hysterectomy for cervical cancer, stage IA1 with lymphovascular invasion, IA2, IB1, IB2, or IIA from 2008 to 2016. Clinicopathologic and perioperative outcomes were compared using appropriate statistical methodologies. Results: Oncologic survival outcomes were analyzed using the Kaplan–Meier method. Among the 105 cases identified, 58 (55.2%) and 47 (44.8%) women underwent MIS and open radical hysterectomy, respectively. Over a median follow-up period of 62 months, women who underwent MIS and open radical hysterectomy had a 5-year overall survival rate of 87.9% and 89.4% (<i>p</i> = 0.845) and a 5-year disease-free survival rate of 82.5% and 86.7% (<i>p</i> = 0.624), respectively. Conclusions: For early-stage cervical cancer, patients who underwent MIS radical hysterectomy had survival outcomes that were comparable to those who underwent open surgery at our institute. |
| first_indexed | 2024-03-10T04:19:21Z |
| format | Article |
| id | doaj.art-d37f2bb4930d45b3a20f5a6093cf3091 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T04:19:21Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-d37f2bb4930d45b3a20f5a6093cf30912023-11-23T07:55:05ZengMDPI AGCancers2072-66942022-04-01149211710.3390/cancers14092117Comparison of Survival Outcomes between Minimally Invasive Surgery and Open Radical Hysterectomy in Early-Stage Cervical CancerI.-Ning Chen0I.-Te Wang1Hsueh-Yu Mu2J.-Timothy Qiu3Wei-Min Liu4Ching-Wen Chang5Yen-Hsieh Chiu6Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei 110301, TaiwanDepartment of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei 110301, TaiwanDepartment of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei 110301, TaiwanDepartment of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei 110301, TaiwanDepartment of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei 110301, TaiwanDepartment of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei 110301, TaiwanDepartment of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei 110301, TaiwanObjectives: To compare the survival outcomes between minimally invasive surgery (MIS) and laparotomy radical hysterectomy in patients with early-stage cervical cancer. Methods: We conducted a retrospective study involving women who received a radical hysterectomy for cervical cancer, stage IA1 with lymphovascular invasion, IA2, IB1, IB2, or IIA from 2008 to 2016. Clinicopathologic and perioperative outcomes were compared using appropriate statistical methodologies. Results: Oncologic survival outcomes were analyzed using the Kaplan–Meier method. Among the 105 cases identified, 58 (55.2%) and 47 (44.8%) women underwent MIS and open radical hysterectomy, respectively. Over a median follow-up period of 62 months, women who underwent MIS and open radical hysterectomy had a 5-year overall survival rate of 87.9% and 89.4% (<i>p</i> = 0.845) and a 5-year disease-free survival rate of 82.5% and 86.7% (<i>p</i> = 0.624), respectively. Conclusions: For early-stage cervical cancer, patients who underwent MIS radical hysterectomy had survival outcomes that were comparable to those who underwent open surgery at our institute.https://www.mdpi.com/2072-6694/14/9/2117cervical cancerhysterectomylaparotomy radical hysterectomyminimally invasive surgerylaparoscopic surgeryrobotic-assisted surgery |
| spellingShingle | I.-Ning Chen I.-Te Wang Hsueh-Yu Mu J.-Timothy Qiu Wei-Min Liu Ching-Wen Chang Yen-Hsieh Chiu Comparison of Survival Outcomes between Minimally Invasive Surgery and Open Radical Hysterectomy in Early-Stage Cervical Cancer Cancers cervical cancer hysterectomy laparotomy radical hysterectomy minimally invasive surgery laparoscopic surgery robotic-assisted surgery |
| title | Comparison of Survival Outcomes between Minimally Invasive Surgery and Open Radical Hysterectomy in Early-Stage Cervical Cancer |
| title_full | Comparison of Survival Outcomes between Minimally Invasive Surgery and Open Radical Hysterectomy in Early-Stage Cervical Cancer |
| title_fullStr | Comparison of Survival Outcomes between Minimally Invasive Surgery and Open Radical Hysterectomy in Early-Stage Cervical Cancer |
| title_full_unstemmed | Comparison of Survival Outcomes between Minimally Invasive Surgery and Open Radical Hysterectomy in Early-Stage Cervical Cancer |
| title_short | Comparison of Survival Outcomes between Minimally Invasive Surgery and Open Radical Hysterectomy in Early-Stage Cervical Cancer |
| title_sort | comparison of survival outcomes between minimally invasive surgery and open radical hysterectomy in early stage cervical cancer |
| topic | cervical cancer hysterectomy laparotomy radical hysterectomy minimally invasive surgery laparoscopic surgery robotic-assisted surgery |
| url | https://www.mdpi.com/2072-6694/14/9/2117 |
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