Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma

Aim: Pleural dissemination of pseudomyxoma peritonei (PMP) is an extremely rare diagnosis, for which no standard therapy is available.Methods: We describe the successful treatment of a 67-year-old male diagnosed with left-sided intrapleural dissemination of PMP (low-grade appendiceal mucinous neopla...

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Main Authors: Viktor Proesmans, Tom Vandaele, Jan Van Slambrouck, Albert Wolthuis, André D´Hoore, Jeroen Dekervel, Eric Van Cutsem, Raphaëla Dresen, Gert De Hertogh, Karlien Degezelle, Dirk Van Raemdonck, Philippe Nafteux, Laurens J. Ceulemans
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:International Journal of Hyperthermia
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/02656736.2022.2104938
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author Viktor Proesmans
Tom Vandaele
Jan Van Slambrouck
Albert Wolthuis
André D´Hoore
Jeroen Dekervel
Eric Van Cutsem
Raphaëla Dresen
Gert De Hertogh
Karlien Degezelle
Dirk Van Raemdonck
Philippe Nafteux
Laurens J. Ceulemans
author_facet Viktor Proesmans
Tom Vandaele
Jan Van Slambrouck
Albert Wolthuis
André D´Hoore
Jeroen Dekervel
Eric Van Cutsem
Raphaëla Dresen
Gert De Hertogh
Karlien Degezelle
Dirk Van Raemdonck
Philippe Nafteux
Laurens J. Ceulemans
author_sort Viktor Proesmans
collection DOAJ
description Aim: Pleural dissemination of pseudomyxoma peritonei (PMP) is an extremely rare diagnosis, for which no standard therapy is available.Methods: We describe the successful treatment of a 67-year-old male diagnosed with left-sided intrapleural dissemination of PMP (low-grade appendiceal mucinous neoplasm), 2 years after treatment of abdominal PMP with cytoreductive surgery (CRS) and hyperthermic intra-peritoneal chemotherapy. Treatment consisted of extended pleural decortication (ePD) and oxaliplatin-based hyperthermic intrathoracic chemotherapy (HITHOC). The patient is doing well without complications or signs of recurrence, 26 months after thoracic surgery.Conclusion: ePD in combination with HITHOC is a valuable treatment for thoracic PMP.
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spelling doaj.art-d3856c70e6c1488bacd87971da5dc8e42022-12-22T02:14:56ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572022-12-013911153115710.1080/02656736.2022.2104938Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxomaViktor Proesmans0Tom Vandaele1Jan Van Slambrouck2Albert Wolthuis3André D´Hoore4Jeroen Dekervel5Eric Van Cutsem6Raphaëla Dresen7Gert De Hertogh8Karlien Degezelle9Dirk Van Raemdonck10Philippe Nafteux11Laurens J. Ceulemans12Department of Thoracic Surgery, University Hospitals Leuven, Leuven, BelgiumDepartment of Thoracic Surgery, University Hospitals Leuven, Leuven, BelgiumDepartment of Thoracic Surgery, University Hospitals Leuven, Leuven, BelgiumDepartment of Abdominal Surgery, University Hospitals Leuven, Leuven, BelgiumDepartment of Abdominal Surgery, University Hospitals Leuven, Leuven, BelgiumDepartment of Gastro-Enterology, University Hospitals Leuven, Leuven, BelgiumDepartment of Gastro-Enterology, University Hospitals Leuven, Leuven, BelgiumDepartment of Radiology, University Hospitals Leuven, Leuven, BelgiumDepartment of Imaging and Pathology, KU Leuven, Leuven, BelgiumDepartment of Cardiac Surgery, Division Perfusion, University Hospitals Leuven, Leuven, BelgiumDepartment of Thoracic Surgery, University Hospitals Leuven, Leuven, BelgiumDepartment of Thoracic Surgery, University Hospitals Leuven, Leuven, BelgiumDepartment of Thoracic Surgery, University Hospitals Leuven, Leuven, BelgiumAim: Pleural dissemination of pseudomyxoma peritonei (PMP) is an extremely rare diagnosis, for which no standard therapy is available.Methods: We describe the successful treatment of a 67-year-old male diagnosed with left-sided intrapleural dissemination of PMP (low-grade appendiceal mucinous neoplasm), 2 years after treatment of abdominal PMP with cytoreductive surgery (CRS) and hyperthermic intra-peritoneal chemotherapy. Treatment consisted of extended pleural decortication (ePD) and oxaliplatin-based hyperthermic intrathoracic chemotherapy (HITHOC). The patient is doing well without complications or signs of recurrence, 26 months after thoracic surgery.Conclusion: ePD in combination with HITHOC is a valuable treatment for thoracic PMP.https://www.tandfonline.com/doi/10.1080/02656736.2022.2104938HITHOCpleural decorticationpseudomyxoma peritonei
spellingShingle Viktor Proesmans
Tom Vandaele
Jan Van Slambrouck
Albert Wolthuis
André D´Hoore
Jeroen Dekervel
Eric Van Cutsem
Raphaëla Dresen
Gert De Hertogh
Karlien Degezelle
Dirk Van Raemdonck
Philippe Nafteux
Laurens J. Ceulemans
Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma
International Journal of Hyperthermia
HITHOC
pleural decortication
pseudomyxoma peritonei
title Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma
title_full Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma
title_fullStr Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma
title_full_unstemmed Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma
title_short Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma
title_sort pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma
topic HITHOC
pleural decortication
pseudomyxoma peritonei
url https://www.tandfonline.com/doi/10.1080/02656736.2022.2104938
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