The Drosophila amyloid precursor protein homologue mediates neuronal survival and neuroglial interactions.
The amyloid precursor protein (APP) is a structurally and functionally conserved transmembrane protein whose physiological role in adult brain function and health is still unclear. Because mutations in APP cause familial Alzheimer's disease (fAD), most research focuses on this aspect of APP bio...
Main Authors: | Irini A Kessissoglou, Dominique Langui, Amr Hasan, Maral Maral, Suchetana B Dutta, Peter Robin Hiesinger, Bassem A Hassan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-12-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3000703 |
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