Comparison of postoperative visual performance between bifocal and trifocal intraocular Lens based on randomized controlled trails: a meta-analysis

Abstract Background To compare the clinical performance of bifocal and trifocal intraocular lenses (IOLs) in cataract surgery, a meta-analysis on randomized controlled trials was conducted. Methods A comprehensive literature retrieval of PubMed, Science Direct and EMBASE was performed in this system...

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Main Authors: Shanshan Jin, David S. Friedman, Kai Cao, Mayinuer Yusufu, Jingshang Zhang, Jinda Wang, Simeng Hou, Guyu Zhu, Bingsong Wang, Ying Xiong, Jing Li, Xiaoxia Li, Hailong He, Xiuhua Wan
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Ophthalmology
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Online Access:http://link.springer.com/article/10.1186/s12886-019-1078-1
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author Shanshan Jin
David S. Friedman
Kai Cao
Mayinuer Yusufu
Jingshang Zhang
Jinda Wang
Simeng Hou
Guyu Zhu
Bingsong Wang
Ying Xiong
Jing Li
Xiaoxia Li
Hailong He
Xiuhua Wan
author_facet Shanshan Jin
David S. Friedman
Kai Cao
Mayinuer Yusufu
Jingshang Zhang
Jinda Wang
Simeng Hou
Guyu Zhu
Bingsong Wang
Ying Xiong
Jing Li
Xiaoxia Li
Hailong He
Xiuhua Wan
author_sort Shanshan Jin
collection DOAJ
description Abstract Background To compare the clinical performance of bifocal and trifocal intraocular lenses (IOLs) in cataract surgery, a meta-analysis on randomized controlled trials was conducted. Methods A comprehensive literature retrieval of PubMed, Science Direct and EMBASE was performed in this systematic review. Clinical outcomes included visual acuity (VA), contrast sensitivity (CS), spectacle independence, postoperative refraction and surgical satisfaction. Results There were 8 RCTs included in this study. The difference of uncorrected near VA (UNVA) between the bifocal IOLs and trifocal IOLs had no significance [MD = 0.02, 95%CI: (− 0.03,0.06)]. There was no significant difference in the distant-corrected near VA (DCNVA) with MD of 0.04 [95%CI (− 0.02, 0.10)]. Compared with trifocal group, the uncorrected intermediate visual acuity (UIVA) [MD = 0.09,95%CI:(0.01,0.17)] was significantly worse in the bifocal group. No difference was found in distance-corrected intermediate VA (DCIVA) [MD = 0.09, 95%CI: (− 0.04, 0.23)] between two groups. Analysis on AT LISA subgroup indicated the bifocal group had worse intermediate VA than trifocal group (AT LISA tri 839 M) [MD = 0.18, 95%CI: (0.12, 0.24) for UIVA and MD = 0.19, 95%CI: (0.13, 0.25) for DCIVA]. However, there was no statistically significant difference between the two groups in the uncorrected distance VA (UDVA) and corrected distance visual acuity (CDVA) [MD = 0.01, 95%CI: (− 0.01,0.04) for UDVA; MD = 0.00, 95%CI: (− 0.01,0.01) for CDVA]. The postoperative refraction of bifocal group was similar to that of trifocal group [MD = -0.08, 95% CI: (− 0.19, 0.03) for spherical equivalent; MD = -0.09, 95%CI: (− 0.21, 0.03) for cylinder; MD = -0.09, 95% CI: (− 0.27, 0.08) for sphere]. No difference was found for spectacle independence, posterior capsular opacification (PCO) incidence and patient satisfaction between bifocal IOLs and trifocal IOLs. [RR = 0.89, 95% CI: (0.71, 1.12) for spectacle independence; RR = 1.81, 95% CI: (0.50, 6.54) for PCO incidence; RR = 0.98, 5% CI: (0.86, 1.12) for patient satisfaction]. Conclusion Patients receiving trifocal IOLs, especially AT LISA tri 839 M, have a better intermediate VA than those receiving bifocal IOLs. Near and distance visual performance, spectacle independence, postoperative refraction and surgical satisfaction of bifocal IOLs were similar to those of trifocal IOLs.
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spelling doaj.art-d38b149cc9a7404ebfde8a83c75426162022-12-22T01:12:58ZengBMCBMC Ophthalmology1471-24152019-03-0119111210.1186/s12886-019-1078-1Comparison of postoperative visual performance between bifocal and trifocal intraocular Lens based on randomized controlled trails: a meta-analysisShanshan Jin0David S. Friedman1Kai Cao2Mayinuer Yusufu3Jingshang Zhang4Jinda Wang5Simeng Hou6Guyu Zhu7Bingsong Wang8Ying Xiong9Jing Li10Xiaoxia Li11Hailong He12Xiuhua Wan13Beijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual SciencesDana Center for Preventive Ophthalmology, The Wilmer Eye Institute, Johns Hopkins University School of MedicineBeijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual SciencesBeijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual SciencesBeijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual SciencesBeijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual SciencesBeijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual SciencesBeijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual SciencesBeijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual SciencesBeijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual SciencesBeijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual SciencesBeijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual SciencesBeijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual SciencesBeijing Institute of Ophthalmology, Beijing Tongren Eye CenterBeijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual SciencesAbstract Background To compare the clinical performance of bifocal and trifocal intraocular lenses (IOLs) in cataract surgery, a meta-analysis on randomized controlled trials was conducted. Methods A comprehensive literature retrieval of PubMed, Science Direct and EMBASE was performed in this systematic review. Clinical outcomes included visual acuity (VA), contrast sensitivity (CS), spectacle independence, postoperative refraction and surgical satisfaction. Results There were 8 RCTs included in this study. The difference of uncorrected near VA (UNVA) between the bifocal IOLs and trifocal IOLs had no significance [MD = 0.02, 95%CI: (− 0.03,0.06)]. There was no significant difference in the distant-corrected near VA (DCNVA) with MD of 0.04 [95%CI (− 0.02, 0.10)]. Compared with trifocal group, the uncorrected intermediate visual acuity (UIVA) [MD = 0.09,95%CI:(0.01,0.17)] was significantly worse in the bifocal group. No difference was found in distance-corrected intermediate VA (DCIVA) [MD = 0.09, 95%CI: (− 0.04, 0.23)] between two groups. Analysis on AT LISA subgroup indicated the bifocal group had worse intermediate VA than trifocal group (AT LISA tri 839 M) [MD = 0.18, 95%CI: (0.12, 0.24) for UIVA and MD = 0.19, 95%CI: (0.13, 0.25) for DCIVA]. However, there was no statistically significant difference between the two groups in the uncorrected distance VA (UDVA) and corrected distance visual acuity (CDVA) [MD = 0.01, 95%CI: (− 0.01,0.04) for UDVA; MD = 0.00, 95%CI: (− 0.01,0.01) for CDVA]. The postoperative refraction of bifocal group was similar to that of trifocal group [MD = -0.08, 95% CI: (− 0.19, 0.03) for spherical equivalent; MD = -0.09, 95%CI: (− 0.21, 0.03) for cylinder; MD = -0.09, 95% CI: (− 0.27, 0.08) for sphere]. No difference was found for spectacle independence, posterior capsular opacification (PCO) incidence and patient satisfaction between bifocal IOLs and trifocal IOLs. [RR = 0.89, 95% CI: (0.71, 1.12) for spectacle independence; RR = 1.81, 95% CI: (0.50, 6.54) for PCO incidence; RR = 0.98, 5% CI: (0.86, 1.12) for patient satisfaction]. Conclusion Patients receiving trifocal IOLs, especially AT LISA tri 839 M, have a better intermediate VA than those receiving bifocal IOLs. Near and distance visual performance, spectacle independence, postoperative refraction and surgical satisfaction of bifocal IOLs were similar to those of trifocal IOLs.http://link.springer.com/article/10.1186/s12886-019-1078-1BifocalTrifocalIntraocular lensesCataract surgeryRandomizedIOLs
spellingShingle Shanshan Jin
David S. Friedman
Kai Cao
Mayinuer Yusufu
Jingshang Zhang
Jinda Wang
Simeng Hou
Guyu Zhu
Bingsong Wang
Ying Xiong
Jing Li
Xiaoxia Li
Hailong He
Xiuhua Wan
Comparison of postoperative visual performance between bifocal and trifocal intraocular Lens based on randomized controlled trails: a meta-analysis
BMC Ophthalmology
Bifocal
Trifocal
Intraocular lenses
Cataract surgery
Randomized
IOLs
title Comparison of postoperative visual performance between bifocal and trifocal intraocular Lens based on randomized controlled trails: a meta-analysis
title_full Comparison of postoperative visual performance between bifocal and trifocal intraocular Lens based on randomized controlled trails: a meta-analysis
title_fullStr Comparison of postoperative visual performance between bifocal and trifocal intraocular Lens based on randomized controlled trails: a meta-analysis
title_full_unstemmed Comparison of postoperative visual performance between bifocal and trifocal intraocular Lens based on randomized controlled trails: a meta-analysis
title_short Comparison of postoperative visual performance between bifocal and trifocal intraocular Lens based on randomized controlled trails: a meta-analysis
title_sort comparison of postoperative visual performance between bifocal and trifocal intraocular lens based on randomized controlled trails a meta analysis
topic Bifocal
Trifocal
Intraocular lenses
Cataract surgery
Randomized
IOLs
url http://link.springer.com/article/10.1186/s12886-019-1078-1
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