Biological Therapy for Asthma
Asthma is a heterogeneous chronic inflammatory disease in the respiratory tract that leads to recurrent episodic symptoms. Study about the mechanism of pathophysiology and immunology which stimulates chronic inflammation in asthma has been greatly developed. The understanding of inflammation mediato...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Universitas Airlangga
2021-01-01
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| Series: | Jurnal Respirasi |
| Subjects: | |
| Online Access: | https://e-journal.unair.ac.id/JR/article/view/23965 |
| _version_ | 1819059679307759616 |
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| author | Resti Yudhawati Megawati Rif’atyyah Nozomi Guntur |
| author_facet | Resti Yudhawati Megawati Rif’atyyah Nozomi Guntur |
| author_sort | Resti Yudhawati |
| collection | DOAJ |
| description | Asthma is a heterogeneous chronic inflammatory disease in the respiratory tract that leads to recurrent episodic symptoms. Study about the mechanism of pathophysiology and immunology which stimulates chronic inflammation in asthma has been greatly developed. The understanding of inflammation mediator that is predominant on various asthma phenotypes could be useful for development of diagnosis and targeted therapy. Standard asthma therapy administered through the airway has limited effects only in the airway. The knowledge of molecular pathophysiology and immunology of this disease developed interest of the drugs that perform proximally from inflammation process in the airway, in this case is biological therapy. Several biological therapies have been investigated for its efficacy on human, including Anti IgE (Omalizumab), Anti Interleukin-5 (Mepolizumab, Reslizumab, Benralizumab), Anti Interleukin-4/Interleukin-13 (Dupilumab), and Anti Interleukin-17 (Secukinumab and Brodalumab). |
| first_indexed | 2024-12-21T14:14:56Z |
| format | Article |
| id | doaj.art-d38c2f2a848641bca3341e4606c14885 |
| institution | Directory Open Access Journal |
| issn | 2407-0831 2621-8372 |
| language | English |
| last_indexed | 2024-12-21T14:14:56Z |
| publishDate | 2021-01-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Jurnal Respirasi |
| spelling | doaj.art-d38c2f2a848641bca3341e4606c148852022-12-21T19:00:56ZengUniversitas AirlanggaJurnal Respirasi2407-08312621-83722021-01-0171273510.20473/jr.v7-I.1.2021.27-3519657Biological Therapy for AsthmaResti Yudhawati0Megawati Rif’atyyah Nozomi Guntur1Universitas AirlanggaUniversitas AirlanggaAsthma is a heterogeneous chronic inflammatory disease in the respiratory tract that leads to recurrent episodic symptoms. Study about the mechanism of pathophysiology and immunology which stimulates chronic inflammation in asthma has been greatly developed. The understanding of inflammation mediator that is predominant on various asthma phenotypes could be useful for development of diagnosis and targeted therapy. Standard asthma therapy administered through the airway has limited effects only in the airway. The knowledge of molecular pathophysiology and immunology of this disease developed interest of the drugs that perform proximally from inflammation process in the airway, in this case is biological therapy. Several biological therapies have been investigated for its efficacy on human, including Anti IgE (Omalizumab), Anti Interleukin-5 (Mepolizumab, Reslizumab, Benralizumab), Anti Interleukin-4/Interleukin-13 (Dupilumab), and Anti Interleukin-17 (Secukinumab and Brodalumab).https://e-journal.unair.ac.id/JR/article/view/23965asthmaomalizumabanti interleukin-5anti interleukin-4/interleukin-13anti interleukin-17. |
| spellingShingle | Resti Yudhawati Megawati Rif’atyyah Nozomi Guntur Biological Therapy for Asthma Jurnal Respirasi asthma omalizumab anti interleukin-5 anti interleukin-4/interleukin-13 anti interleukin-17. |
| title | Biological Therapy for Asthma |
| title_full | Biological Therapy for Asthma |
| title_fullStr | Biological Therapy for Asthma |
| title_full_unstemmed | Biological Therapy for Asthma |
| title_short | Biological Therapy for Asthma |
| title_sort | biological therapy for asthma |
| topic | asthma omalizumab anti interleukin-5 anti interleukin-4/interleukin-13 anti interleukin-17. |
| url | https://e-journal.unair.ac.id/JR/article/view/23965 |
| work_keys_str_mv | AT restiyudhawati biologicaltherapyforasthma AT megawatirifatyyahnozomiguntur biologicaltherapyforasthma |