HLA-G 14bp Ins/Del Polymorphism, Plasma Level of Soluble HLA-G, and Association with IL-6/IL-10 Ratio and Survival of Glioma Patients

HLA-G 14bp Ins/Del Polymorphism, Plasma Level of Soluble HLA-G, and Association with IL-6/IL-10 Ratio and Survival of Glioma Patients

HLA-G is an immune checkpoint molecule with immunosuppressive and anti-inflammatory activities, and its expression and level of its soluble form (sHLA-G) may play an important role in tumor prognosis. The HLA-G 14bp ins/del polymorphism and the plasma level of soluble HLA-G (sHLA-G) were investigate...

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Bibliographic Details
Main Authors: Maria Bucova, Kristina Kluckova, Jan Kozak, Boris Rychly, Magda Suchankova, Marian Svajdler, Viktor Matejcik, Juraj Steno, Eszter Zsemlye, Vladimira Durmanova
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Diagnostics
Subjects:
glioma
HLA-G
IL-6
polymorphism
prognosis
survival
Online Access:https://www.mdpi.com/2075-4418/12/5/1099

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