The Role of Pyrazolopyridine Derivatives on Different Steps of Herpes Simplex Virus Type-1 <i>In Vitro</i> Replicative Cycle

The Role of Pyrazolopyridine Derivatives on Different Steps of Herpes Simplex Virus Type-1 <i>In Vitro</i> Replicative Cycle

Herpes simplex virus type-1 (HSV-1) infection causes several disorders, and acyclovir is used as a reference compound. However, resistant strains are commonly observed. Herein, we investigate the effects of <i>N</i>-heterocyclic compounds (pyrazolopyridine derivatives), named <b>AR...

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Bibliographic Details
Main Authors: Milene D. Miranda, Otávio Augusto Chaves, Alice S. Rosa, Alexandre R. Azevedo, Luiz Carlos da Silva Pinheiro, Vinicius C. Soares, Suelen S. G. Dias, Juliana L. Abrantes, Alice Maria R. Bernardino, Izabel C. P. Paixão, Thiago Moreno L. Souza, Carlos Frederico L. Fontes
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
pyrazolopyridine
antiviral
molecular docking
HSV-1
ICP-27
gD
Online Access:https://www.mdpi.com/1422-0067/23/15/8135

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https://www.mdpi.com/1422-0067/23/15/8135

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