Structure-Aware Mycobacterium tuberculosis Functional Annotation Uncloaks Resistance, Metabolic, and Virulence Genes

Structure-Aware Mycobacterium tuberculosis Functional Annotation Uncloaks Resistance, Metabolic, and Virulence Genes

ABSTRACT Accurate and timely functional genome annotation is essential for translating basic pathogen research into clinically impactful advances. Here, through literature curation and structure-function inference, we systematically update the functional genome annotation of Mycobacterium tuberculos...

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Bibliographic Details
Main Authors: Samuel J. Modlin, Afif Elghraoui, Deepika Gunasekaran, Alyssa M. Zlotnicki, Nicholas A. Dillon, Nermeeta Dhillon, Norman Kuo, Cassidy Robinhold, Carmela K. Chan, Anthony D. Baughn, Faramarz Valafar
Format: Article
Language:English
Published: American Society for Microbiology 2021-12-01
Series:mSystems
Subjects:
Mycobacterium tuberculosis
annotation
structure
virulence factors
functional genomics
pyrazinamide
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00673-21

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