Heart rate and blood pressure in male Ts65Dn mice: a model to investigate cardiovascular responses in Down syndrome
Abstract Down syndrome (Ds) is the most common chromosomal cause of intellectual disability that results from triplication of chromosome 21 genes. Lower blood pressure (BP) and heart rate (HR) in response to exercise and other stressors are prevalent in Ds, and are mediated by autonomic dysfunction....
Main Authors: | Lara R. DeRuisseau, Candace N. Receno, Kevin S. Heffernan, Caitlin M. Cunningham |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-09-01
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Series: | Physiological Reports |
Subjects: | |
Online Access: | https://doi.org/10.14814/phy2.14205 |
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