Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance

Innate immunity is critical in the response to bacterial infection. Here the authors show a role for the nucleolar-associated protein fibrillarin in regulating the innate response to infection.

Bibliographic Details
Main Authors: Varnesh Tiku, Chun Kew, Parul Mehrotra, Raja Ganesan, Nirmal Robinson, Adam Antebi
Format: Article
Language:English
Published: Nature Portfolio 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06051-1
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author Varnesh Tiku
Chun Kew
Parul Mehrotra
Raja Ganesan
Nirmal Robinson
Adam Antebi
author_facet Varnesh Tiku
Chun Kew
Parul Mehrotra
Raja Ganesan
Nirmal Robinson
Adam Antebi
author_sort Varnesh Tiku
collection DOAJ
description Innate immunity is critical in the response to bacterial infection. Here the authors show a role for the nucleolar-associated protein fibrillarin in regulating the innate response to infection.
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spelling doaj.art-d39487d3ea934fb19b4c747f4667d6e52022-12-21T18:32:00ZengNature PortfolioNature Communications2041-17232018-09-019111010.1038/s41467-018-06051-1Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistanceVarnesh Tiku0Chun Kew1Parul Mehrotra2Raja Ganesan3Nirmal Robinson4Adam Antebi5Max Planck Institute for Biology of AgeingMax Planck Institute for Biology of AgeingMax Planck Institute for Biology of AgeingCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of CologneCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of CologneMax Planck Institute for Biology of AgeingInnate immunity is critical in the response to bacterial infection. Here the authors show a role for the nucleolar-associated protein fibrillarin in regulating the innate response to infection.https://doi.org/10.1038/s41467-018-06051-1
spellingShingle Varnesh Tiku
Chun Kew
Parul Mehrotra
Raja Ganesan
Nirmal Robinson
Adam Antebi
Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance
Nature Communications
title Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance
title_full Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance
title_fullStr Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance
title_full_unstemmed Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance
title_short Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance
title_sort nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance
url https://doi.org/10.1038/s41467-018-06051-1
work_keys_str_mv AT varneshtiku nucleolarfibrillarinisanevolutionarilyconservedregulatorofbacterialpathogenresistance
AT chunkew nucleolarfibrillarinisanevolutionarilyconservedregulatorofbacterialpathogenresistance
AT parulmehrotra nucleolarfibrillarinisanevolutionarilyconservedregulatorofbacterialpathogenresistance
AT rajaganesan nucleolarfibrillarinisanevolutionarilyconservedregulatorofbacterialpathogenresistance
AT nirmalrobinson nucleolarfibrillarinisanevolutionarilyconservedregulatorofbacterialpathogenresistance
AT adamantebi nucleolarfibrillarinisanevolutionarilyconservedregulatorofbacterialpathogenresistance