Growth Inhibition and Apoptotic Effect of Pine Extract and Abietic Acid on MCF-7 Breast Cancer Cells via Alteration of Multiple Gene Expressions Using In Vitro Approach

Growth Inhibition and Apoptotic Effect of Pine Extract and Abietic Acid on MCF-7 Breast Cancer Cells via Alteration of Multiple Gene Expressions Using In Vitro Approach

In vitro anti-proliferative activity of <i>Pinus palustris</i> extract and its purified abietic acid was assessed against different human cancer cell lines (HepG-2, MCF-7 and HCT-116) compared to normal WI-38 cell line. Abietic acid showed more promising IC<sub>50</sub> value...

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Bibliographic Details
Main Authors: Hesham Haffez, Shimaa Osman, Hassan Y. Ebrahim, Zeinab A. Hassan
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
abietic aid
P. palustris
anti-cancer
MCF-7
apoptosis
Online Access:https://www.mdpi.com/1420-3049/27/1/293

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