Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia
In this research, silver-seeded PVC was synthesised and modified to combat ventilator-associated pneumonia by preventing bacterial adherence. The silver-seeded PVC was synthesised by in situ deposition of silver particles, and the silver-seeded PVC was further modified by reacting with 3,3,4,4,5,5,6...
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Format: | Article |
Language: | English |
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University of Huddersfield Press
2022-11-01
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Series: | British Journal of Pharmacy |
Subjects: | |
Online Access: | https://www.bjpharm.org.uk/article/id/1126/ |
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author | Jia Li Matthew Wylie Colin P McCoy |
author_facet | Jia Li Matthew Wylie Colin P McCoy |
author_sort | Jia Li |
collection | DOAJ |
description | In this research, silver-seeded PVC was synthesised and modified to combat ventilator-associated pneumonia by preventing bacterial adherence. The silver-seeded PVC was synthesised by in situ deposition of silver particles, and the silver-seeded PVC was further modified by reacting with 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanethiol to create a superhydrophobic surface with static water contact angle more than 150°. The silver-coated PVC and superhydrophobic silver-coated PVC both exhibited excellent anti-adherent activity against MRSA and Pseudomonas aeruginosa. |
first_indexed | 2024-03-13T10:51:39Z |
format | Article |
id | doaj.art-d39d3b5b88414ae182e258b103e4fe83 |
institution | Directory Open Access Journal |
issn | 2058-8356 |
language | English |
last_indexed | 2024-03-13T10:51:39Z |
publishDate | 2022-11-01 |
publisher | University of Huddersfield Press |
record_format | Article |
series | British Journal of Pharmacy |
spelling | doaj.art-d39d3b5b88414ae182e258b103e4fe832023-05-17T13:10:56ZengUniversity of Huddersfield PressBritish Journal of Pharmacy2058-83562022-11-017210.5920/bjpharm.1126Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumoniaJia Li0Matthew Wylie1Colin P McCoy2Queen's University BelfastQueen's University BelfastQueen's University BelfastIn this research, silver-seeded PVC was synthesised and modified to combat ventilator-associated pneumonia by preventing bacterial adherence. The silver-seeded PVC was synthesised by in situ deposition of silver particles, and the silver-seeded PVC was further modified by reacting with 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanethiol to create a superhydrophobic surface with static water contact angle more than 150°. The silver-coated PVC and superhydrophobic silver-coated PVC both exhibited excellent anti-adherent activity against MRSA and Pseudomonas aeruginosa.https://www.bjpharm.org.uk/article/id/1126/pvcsuperhydrophobicanti-adherencevap |
spellingShingle | Jia Li Matthew Wylie Colin P McCoy Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia British Journal of Pharmacy pvc superhydrophobic anti-adherence vap |
title | Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia |
title_full | Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia |
title_fullStr | Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia |
title_full_unstemmed | Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia |
title_short | Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia |
title_sort | synthesis and modification of silver seeded pvc for use as anti adherent materials to prevent ventilator associated pneumonia |
topic | pvc superhydrophobic anti-adherence vap |
url | https://www.bjpharm.org.uk/article/id/1126/ |
work_keys_str_mv | AT jiali synthesisandmodificationofsilverseededpvcforuseasantiadherentmaterialstopreventventilatorassociatedpneumonia AT matthewwylie synthesisandmodificationofsilverseededpvcforuseasantiadherentmaterialstopreventventilatorassociatedpneumonia AT colinpmccoy synthesisandmodificationofsilverseededpvcforuseasantiadherentmaterialstopreventventilatorassociatedpneumonia |