Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia

In this research, silver-seeded PVC was synthesised and modified to combat ventilator-associated pneumonia by preventing bacterial adherence. The silver-seeded PVC was synthesised by in situ deposition of silver particles, and the silver-seeded PVC was further modified by reacting with 3,3,4,4,5,5,6...

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Main Authors: Jia Li, Matthew Wylie, Colin P McCoy
Format: Article
Language:English
Published: University of Huddersfield Press 2022-11-01
Series:British Journal of Pharmacy
Subjects:
Online Access:https://www.bjpharm.org.uk/article/id/1126/
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author Jia Li
Matthew Wylie
Colin P McCoy
author_facet Jia Li
Matthew Wylie
Colin P McCoy
author_sort Jia Li
collection DOAJ
description In this research, silver-seeded PVC was synthesised and modified to combat ventilator-associated pneumonia by preventing bacterial adherence. The silver-seeded PVC was synthesised by in situ deposition of silver particles, and the silver-seeded PVC was further modified by reacting with 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanethiol to create a superhydrophobic surface with static water contact angle more than 150°. The silver-coated PVC and superhydrophobic silver-coated PVC both exhibited excellent anti-adherent activity against MRSA and Pseudomonas aeruginosa.
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spelling doaj.art-d39d3b5b88414ae182e258b103e4fe832023-05-17T13:10:56ZengUniversity of Huddersfield PressBritish Journal of Pharmacy2058-83562022-11-017210.5920/bjpharm.1126Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumoniaJia Li0Matthew Wylie1Colin P McCoy2Queen's University BelfastQueen's University BelfastQueen's University BelfastIn this research, silver-seeded PVC was synthesised and modified to combat ventilator-associated pneumonia by preventing bacterial adherence. The silver-seeded PVC was synthesised by in situ deposition of silver particles, and the silver-seeded PVC was further modified by reacting with 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanethiol to create a superhydrophobic surface with static water contact angle more than 150°. The silver-coated PVC and superhydrophobic silver-coated PVC both exhibited excellent anti-adherent activity against MRSA and Pseudomonas aeruginosa.https://www.bjpharm.org.uk/article/id/1126/pvcsuperhydrophobicanti-adherencevap
spellingShingle Jia Li
Matthew Wylie
Colin P McCoy
Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia
British Journal of Pharmacy
pvc
superhydrophobic
anti-adherence
vap
title Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia
title_full Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia
title_fullStr Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia
title_full_unstemmed Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia
title_short Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia
title_sort synthesis and modification of silver seeded pvc for use as anti adherent materials to prevent ventilator associated pneumonia
topic pvc
superhydrophobic
anti-adherence
vap
url https://www.bjpharm.org.uk/article/id/1126/
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AT colinpmccoy synthesisandmodificationofsilverseededpvcforuseasantiadherentmaterialstopreventventilatorassociatedpneumonia