Screening for antibacterial, antifungal and cytotoxic agents in three hard coral species from Persian Gulf
Within the frame of a biodiversity and bioactivity study of marine macro organisms from the Persian Gulf, three hard coral species extracts were investigated for cytotoxic, antibacterial and antifungal activities against five human pathogenic microorganisms. All concentrations of extracts from three...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Bangladesh Pharmacological Society
2014-04-01
|
| Series: | Bangladesh Journal of Pharmacology |
| Subjects: | |
| Online Access: | https://www.banglajol.info/index.php/BJP/article/view/17825 |
| _version_ | 1818752863744032768 |
|---|---|
| author | Flora Mohamadizadeh Majid Afkhami Maryam Ehsanpour Amir Houshang Bahri |
| author_facet | Flora Mohamadizadeh Majid Afkhami Maryam Ehsanpour Amir Houshang Bahri |
| author_sort | Flora Mohamadizadeh |
| collection | DOAJ |
| description | Within the frame of a biodiversity and bioactivity study of marine macro organisms from the Persian Gulf, three hard coral species extracts were investigated for cytotoxic, antibacterial and antifungal activities against five human pathogenic microorganisms. All concentrations of extracts from three hard corals showed no antifungal activity towards the tested strains. In antibacterial assays the hard coral extracts showed significant activity solely against Staphylococcus aureus with MICs ranging from 3 to 9 mcg/mL. The highest antibacterial activity was found in the aqueous methanol extract of Porites compressa with an inhibition zone of 22 mm against Staphylococcus aureus at 18 ?g/mL extract concentration. It is important for future research to concentrate on finding the mechanisms employed by corals to defend themselves against invasion, the mechanism of infections and the type of chemical compounds in coral extracts that inhibit antibacterial growth or proliferation in underexplored areas such as the Persian Gulf. |
| first_indexed | 2024-12-18T04:58:14Z |
| format | Article |
| id | doaj.art-d39d5e6105a8435cb711df8dab4629d1 |
| institution | Directory Open Access Journal |
| issn | 1991-0088 |
| language | English |
| last_indexed | 2024-12-18T04:58:14Z |
| publishDate | 2014-04-01 |
| publisher | Bangladesh Pharmacological Society |
| record_format | Article |
| series | Bangladesh Journal of Pharmacology |
| spelling | doaj.art-d39d5e6105a8435cb711df8dab4629d12022-12-21T21:20:13ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882014-04-0192Screening for antibacterial, antifungal and cytotoxic agents in three hard coral species from Persian GulfFlora Mohamadizadeh0Majid Afkhami1Maryam Ehsanpour2Amir Houshang Bahri3Islamic Azad University, Bandar Abbas Branch, P.O.Box:79159-1311, Bandar AbbasIslamic Azad University, Bandar Abbas Branch, P.O.Box:79159-1311, Bandar Abbas, IranIslamic Azad University, Bandar Abbas Branch, P.O.Box:79159-1311, Bandar Abbas, IranIslamic Azad University, Bandar Abbas Branch, P.O.Box:79159-1311, Bandar Abbas, IranWithin the frame of a biodiversity and bioactivity study of marine macro organisms from the Persian Gulf, three hard coral species extracts were investigated for cytotoxic, antibacterial and antifungal activities against five human pathogenic microorganisms. All concentrations of extracts from three hard corals showed no antifungal activity towards the tested strains. In antibacterial assays the hard coral extracts showed significant activity solely against Staphylococcus aureus with MICs ranging from 3 to 9 mcg/mL. The highest antibacterial activity was found in the aqueous methanol extract of Porites compressa with an inhibition zone of 22 mm against Staphylococcus aureus at 18 ?g/mL extract concentration. It is important for future research to concentrate on finding the mechanisms employed by corals to defend themselves against invasion, the mechanism of infections and the type of chemical compounds in coral extracts that inhibit antibacterial growth or proliferation in underexplored areas such as the Persian Gulf.https://www.banglajol.info/index.php/BJP/article/view/17825antibacterialantifungalcytotoxic |
| spellingShingle | Flora Mohamadizadeh Majid Afkhami Maryam Ehsanpour Amir Houshang Bahri Screening for antibacterial, antifungal and cytotoxic agents in three hard coral species from Persian Gulf Bangladesh Journal of Pharmacology antibacterial antifungal cytotoxic |
| title | Screening for antibacterial, antifungal and cytotoxic agents in three hard coral species from Persian Gulf |
| title_full | Screening for antibacterial, antifungal and cytotoxic agents in three hard coral species from Persian Gulf |
| title_fullStr | Screening for antibacterial, antifungal and cytotoxic agents in three hard coral species from Persian Gulf |
| title_full_unstemmed | Screening for antibacterial, antifungal and cytotoxic agents in three hard coral species from Persian Gulf |
| title_short | Screening for antibacterial, antifungal and cytotoxic agents in three hard coral species from Persian Gulf |
| title_sort | screening for antibacterial antifungal and cytotoxic agents in three hard coral species from persian gulf |
| topic | antibacterial antifungal cytotoxic |
| url | https://www.banglajol.info/index.php/BJP/article/view/17825 |
| work_keys_str_mv | AT floramohamadizadeh screeningforantibacterialantifungalandcytotoxicagentsinthreehardcoralspeciesfrompersiangulf AT majidafkhami screeningforantibacterialantifungalandcytotoxicagentsinthreehardcoralspeciesfrompersiangulf AT maryamehsanpour screeningforantibacterialantifungalandcytotoxicagentsinthreehardcoralspeciesfrompersiangulf AT amirhoushangbahri screeningforantibacterialantifungalandcytotoxicagentsinthreehardcoralspeciesfrompersiangulf |