A Clinical Case of Out-of-Hospital Cardiac Arrest and Post-Resuscitation Disease in a Patient with Acute Myocardial Infarction
Background. Prediction of survival in adult patients after out-of-hospital cardiopulmonary resuscitation remains a difficult issue. This clinical case describes our experience of managing a patient after an out-of-hospital cardiac arrest due to an acute coronary syndrome with the development of post...
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| Format: | Article |
| Language: | English |
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Professional Edition Eastern Europe
2023-12-01
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| Series: | Український журнал серцево-судинної хірургії |
| Subjects: | |
| Online Access: | http://cvs.org.ua/index.php/ujcvs/article/view/616 |
| _version_ | 1797371796940390400 |
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| author | Andriy P. Mazur Elina I. Novikova Natalia O. Kuzminova |
| author_facet | Andriy P. Mazur Elina I. Novikova Natalia O. Kuzminova |
| author_sort | Andriy P. Mazur |
| collection | DOAJ |
| description | Background. Prediction of survival in adult patients after out-of-hospital cardiopulmonary resuscitation remains a difficult issue. This clinical case describes our experience of managing a patient after an out-of-hospital cardiac arrest due to an acute coronary syndrome with the development of postanoxic coma, with subsequent successful restoration of neurological function.
Case description. Patient K., a 48-year-old man, was delivered unconscious (Glasgow Coma Scale score 7) without spontaneous breathing. During transportation to the hospital, ventricular fibrillation occurred, cardiopulmonary resuscitation lasting 1 hour was performed with restoration of sinus rhythm. Diagnosis: acute coronary syndrome with ST segment elevation; cardiogenic shock; condition after cardiopulmonary resuscitation. Stenting of the occluded circumflex artery was performed. During the patient’s stay in the intensive care unit (ICU), hemodynamics and laboratory tests were carefully monitored and no significant systemic disorders were detected. The patient stayed in the ICU for 19 days. At the time of discharge, the general condition was relatively satisfactory, Glasgow Coma Scale score was 14-15, with minimal neurological deficit. The patient was transferred to a neurological department for further rehabilitation.
Results. Determining the probability of either good or bad outcome in comatose patients after cardiac arrest is one of the most important steps in treatment after stabilization of the heart activity. Recent data confirm the utility of electroencephalography (EEG) monitoring for prognosis. The pattern of response to sedative drugs may provide prognostic information. In this clinical case, when EEG was recorded during sedation, preservation of the response to stimuli was registered, and 48 hours after disconnection, patterns corresponding to awakening were registered, which was considered as a positive prognostic sign.
Conclusions. In adult patients after cardiopulmonary resuscitation with postanoxic coma, clinical, neurophysiological and radiological tests predict poor neurologic outcome within the first week after cardiac arrest with a certain percentage of false positive rate. However, most predictors have low sensitivity and specificity. Accurate prognosing requires a comprehensive approach. Neurological examination remains the gold standard, but its result is affected by the effect of sedative drugs used in critical patients in the ICU. The use of EEG increases the accuracy of the prognosing. |
| first_indexed | 2024-03-08T18:26:10Z |
| format | Article |
| id | doaj.art-d39d637bfd26491cb3f58423bc85d028 |
| institution | Directory Open Access Journal |
| issn | 2664-5963 2664-5971 |
| language | English |
| last_indexed | 2024-03-08T18:26:10Z |
| publishDate | 2023-12-01 |
| publisher | Professional Edition Eastern Europe |
| record_format | Article |
| series | Український журнал серцево-судинної хірургії |
| spelling | doaj.art-d39d637bfd26491cb3f58423bc85d0282023-12-30T12:07:56ZengProfessional Edition Eastern EuropeУкраїнський журнал серцево-судинної хірургії2664-59632664-59712023-12-0131412112510.30702/ujcvs/23.31(04)/MN022-12112616A Clinical Case of Out-of-Hospital Cardiac Arrest and Post-Resuscitation Disease in a Patient with Acute Myocardial InfarctionAndriy P. Mazur0https://orcid.org/0000-0002-6873-7573Elina I. Novikova1https://orcid.org/0000-0002-2105-6623Natalia O. Kuzminova2https://orcid.org/0009-0001-0329-8039National Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine, Kyiv, UkraineNational Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine, Kyiv, UkraineNational Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine, Kyiv, UkraineBackground. Prediction of survival in adult patients after out-of-hospital cardiopulmonary resuscitation remains a difficult issue. This clinical case describes our experience of managing a patient after an out-of-hospital cardiac arrest due to an acute coronary syndrome with the development of postanoxic coma, with subsequent successful restoration of neurological function. Case description. Patient K., a 48-year-old man, was delivered unconscious (Glasgow Coma Scale score 7) without spontaneous breathing. During transportation to the hospital, ventricular fibrillation occurred, cardiopulmonary resuscitation lasting 1 hour was performed with restoration of sinus rhythm. Diagnosis: acute coronary syndrome with ST segment elevation; cardiogenic shock; condition after cardiopulmonary resuscitation. Stenting of the occluded circumflex artery was performed. During the patient’s stay in the intensive care unit (ICU), hemodynamics and laboratory tests were carefully monitored and no significant systemic disorders were detected. The patient stayed in the ICU for 19 days. At the time of discharge, the general condition was relatively satisfactory, Glasgow Coma Scale score was 14-15, with minimal neurological deficit. The patient was transferred to a neurological department for further rehabilitation. Results. Determining the probability of either good or bad outcome in comatose patients after cardiac arrest is one of the most important steps in treatment after stabilization of the heart activity. Recent data confirm the utility of electroencephalography (EEG) monitoring for prognosis. The pattern of response to sedative drugs may provide prognostic information. In this clinical case, when EEG was recorded during sedation, preservation of the response to stimuli was registered, and 48 hours after disconnection, patterns corresponding to awakening were registered, which was considered as a positive prognostic sign. Conclusions. In adult patients after cardiopulmonary resuscitation with postanoxic coma, clinical, neurophysiological and radiological tests predict poor neurologic outcome within the first week after cardiac arrest with a certain percentage of false positive rate. However, most predictors have low sensitivity and specificity. Accurate prognosing requires a comprehensive approach. Neurological examination remains the gold standard, but its result is affected by the effect of sedative drugs used in critical patients in the ICU. The use of EEG increases the accuracy of the prognosing.http://cvs.org.ua/index.php/ujcvs/article/view/616postanoxic comacardiopulmonary resuscitationacute coronary syndromeacute left ventricular failurecardiogenic shockventricular fibrillationelectroencephalography |
| spellingShingle | Andriy P. Mazur Elina I. Novikova Natalia O. Kuzminova A Clinical Case of Out-of-Hospital Cardiac Arrest and Post-Resuscitation Disease in a Patient with Acute Myocardial Infarction Український журнал серцево-судинної хірургії postanoxic coma cardiopulmonary resuscitation acute coronary syndrome acute left ventricular failure cardiogenic shock ventricular fibrillation electroencephalography |
| title | A Clinical Case of Out-of-Hospital Cardiac Arrest and Post-Resuscitation Disease in a Patient with Acute Myocardial Infarction |
| title_full | A Clinical Case of Out-of-Hospital Cardiac Arrest and Post-Resuscitation Disease in a Patient with Acute Myocardial Infarction |
| title_fullStr | A Clinical Case of Out-of-Hospital Cardiac Arrest and Post-Resuscitation Disease in a Patient with Acute Myocardial Infarction |
| title_full_unstemmed | A Clinical Case of Out-of-Hospital Cardiac Arrest and Post-Resuscitation Disease in a Patient with Acute Myocardial Infarction |
| title_short | A Clinical Case of Out-of-Hospital Cardiac Arrest and Post-Resuscitation Disease in a Patient with Acute Myocardial Infarction |
| title_sort | clinical case of out of hospital cardiac arrest and post resuscitation disease in a patient with acute myocardial infarction |
| topic | postanoxic coma cardiopulmonary resuscitation acute coronary syndrome acute left ventricular failure cardiogenic shock ventricular fibrillation electroencephalography |
| url | http://cvs.org.ua/index.php/ujcvs/article/view/616 |
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