Minimal sufficient balance randomization for sequential randomized controlled trial designs: results from the ESCAPE trial

Minimal sufficient balance randomization for sequential randomized controlled trial designs: results from the ESCAPE trial

Abstract Background We describe the implementation of minimal sufficient balance randomization, a covariate-adaptive randomization technique, used for the “Endovascular treatment for Small Core and Anterior circulation Proximal occlusion with Emphasis on minimizing CT to recanalization times” (ESCAP...

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Bibliographic Details
Main Authors: Tolulope T. Sajobi, Gurbakhshash Singh, Mark W. Lowerison, Jordan Engbers, Bijoy K. Menon, Andrew M. Demchuk, Mayank Goyal, Michael D. Hill
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Trials
Subjects:
Minimal sufficient balance
Randomization
Stroke trial
Endovascular therapy
Data monitoring
Online Access:http://link.springer.com/article/10.1186/s13063-017-2264-1

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