Separable gain control of ongoing and evoked activity in the visual cortex by serotonergic input

Separable gain control of ongoing and evoked activity in the visual cortex by serotonergic input

Controlling gain of cortical activity is essential to modulate weights between internal ongoing communication and external sensory drive. Here, we show that serotonergic input has separable suppressive effects on the gain of ongoing and evoked visual activity. We combined optogenetic stimulation of...

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Bibliographic Details
Main Authors: Zohre Azimi, Ruxandra Barzan, Katharina Spoida, Tatjana Surdin, Patric Wollenweber, Melanie D Mark, Stefan Herlitze, Dirk Jancke
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-04-01
Series:eLife
Subjects:
serotonergic receptors
calcium imaging
integration of cortical activity
ongoing activity
contrast normalization
optogenetics
Online Access:https://elifesciences.org/articles/53552

Internet

https://elifesciences.org/articles/53552

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