Physical inactivity and cognitive impairment in Korean older adults: gender differences in potential covariates
Background: Physical inactivity is one major lifestyle risk factor of mild cognitive impairment with ageing. Aim: To investigate whether or not potential covariates modulate the association between physical activity (PA) and cognitive impairment in older adults. Subjects and methods: Data from 10 24...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2017-11-01
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| Series: | Annals of Human Biology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/03014460.2017.1392604 |
| _version_ | 1797685597644521472 |
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| author | Jinkyung Cho Youngyun Jin Inhwan Lee Haeryun Hong Donghyun Kim Soohyun Park Hyunsik Kang |
| author_facet | Jinkyung Cho Youngyun Jin Inhwan Lee Haeryun Hong Donghyun Kim Soohyun Park Hyunsik Kang |
| author_sort | Jinkyung Cho |
| collection | DOAJ |
| description | Background: Physical inactivity is one major lifestyle risk factor of mild cognitive impairment with ageing. Aim: To investigate whether or not potential covariates modulate the association between physical activity (PA) and cognitive impairment in older adults. Subjects and methods: Data from 10 245 Korean older adults (5817 women) were used. Results: High PA older adults were younger and longer educated and had lower comorbidity and depression than low PA older adults. Compared with low PA men, moderate PA men only had a significantly lower odds-ratio (OR) and 95% confidence interval (95% CI) (OR = 0.795, 95% CI = 0.654 ∼ 0.965, p = 0.021) for having cognitive impairment, even after adjusting for measured covariates, which was no longer significant when additionally adjusted for comorbidity (OR = 0.862, 95% CI = 0.707 ∼ 1.051, p = 0.143). Compared with low PA women, moderate and high PA women had significantly lower risks of cognitive impairment (OR = 0.830, 95% CI = 0.712 ∼ 0.969, p = 0.018 and OR = 0.784, 95% CI = 0.651 ∼ 0.943, p = 0.010, respectively), even after adjusting for the measured covariates including comorbidity, which was no longer significant when additionally adjusted for depression (OR = 0.897, 95% CI = 0.776 ∼ 1.049, p = 0.173 and OR = 0.919, 95% CI = 0.761 ∼ 1.111, p = 0.385, respectively). Conclusion: These findings suggest that gender differences in the covariates modulate the relationship between physical activity and cognitive decline in older Korean adults. |
| first_indexed | 2024-03-12T00:47:26Z |
| format | Article |
| id | doaj.art-d3a016454a914ee8ba2031747f754184 |
| institution | Directory Open Access Journal |
| issn | 0301-4460 1464-5033 |
| language | English |
| last_indexed | 2024-03-12T00:47:26Z |
| publishDate | 2017-11-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Human Biology |
| spelling | doaj.art-d3a016454a914ee8ba2031747f7541842023-09-14T15:36:09ZengTaylor & Francis GroupAnnals of Human Biology0301-44601464-50332017-11-0144872973710.1080/03014460.2017.13926041392604Physical inactivity and cognitive impairment in Korean older adults: gender differences in potential covariatesJinkyung Cho0Youngyun Jin1Inhwan Lee2Haeryun Hong3Donghyun Kim4Soohyun Park5Hyunsik Kang6Sungkyunkwan UniversitySungkyunkwan UniversitySungkyunkwan UniversitySungkyunkwan UniversitySungkyunkwan UniversitySungkyunkwan UniversitySungkyunkwan UniversityBackground: Physical inactivity is one major lifestyle risk factor of mild cognitive impairment with ageing. Aim: To investigate whether or not potential covariates modulate the association between physical activity (PA) and cognitive impairment in older adults. Subjects and methods: Data from 10 245 Korean older adults (5817 women) were used. Results: High PA older adults were younger and longer educated and had lower comorbidity and depression than low PA older adults. Compared with low PA men, moderate PA men only had a significantly lower odds-ratio (OR) and 95% confidence interval (95% CI) (OR = 0.795, 95% CI = 0.654 ∼ 0.965, p = 0.021) for having cognitive impairment, even after adjusting for measured covariates, which was no longer significant when additionally adjusted for comorbidity (OR = 0.862, 95% CI = 0.707 ∼ 1.051, p = 0.143). Compared with low PA women, moderate and high PA women had significantly lower risks of cognitive impairment (OR = 0.830, 95% CI = 0.712 ∼ 0.969, p = 0.018 and OR = 0.784, 95% CI = 0.651 ∼ 0.943, p = 0.010, respectively), even after adjusting for the measured covariates including comorbidity, which was no longer significant when additionally adjusted for depression (OR = 0.897, 95% CI = 0.776 ∼ 1.049, p = 0.173 and OR = 0.919, 95% CI = 0.761 ∼ 1.111, p = 0.385, respectively). Conclusion: These findings suggest that gender differences in the covariates modulate the relationship between physical activity and cognitive decline in older Korean adults.http://dx.doi.org/10.1080/03014460.2017.1392604agingphysical activitycognitiondepressionkorean |
| spellingShingle | Jinkyung Cho Youngyun Jin Inhwan Lee Haeryun Hong Donghyun Kim Soohyun Park Hyunsik Kang Physical inactivity and cognitive impairment in Korean older adults: gender differences in potential covariates Annals of Human Biology aging physical activity cognition depression korean |
| title | Physical inactivity and cognitive impairment in Korean older adults: gender differences in potential covariates |
| title_full | Physical inactivity and cognitive impairment in Korean older adults: gender differences in potential covariates |
| title_fullStr | Physical inactivity and cognitive impairment in Korean older adults: gender differences in potential covariates |
| title_full_unstemmed | Physical inactivity and cognitive impairment in Korean older adults: gender differences in potential covariates |
| title_short | Physical inactivity and cognitive impairment in Korean older adults: gender differences in potential covariates |
| title_sort | physical inactivity and cognitive impairment in korean older adults gender differences in potential covariates |
| topic | aging physical activity cognition depression korean |
| url | http://dx.doi.org/10.1080/03014460.2017.1392604 |
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