Changes in minimum inhibitory concentration of levofloxacin for Escherichia coli strains isolated from urine samples in mainland China, 2004 to 2014
Eschrichia coli urinary isolates were collected from 20 Chinese hospitals during five 1-year periods from 2004 to 2014. The susceptibility of E. coli to levofloxacin has remained stable during the past 11 years, and 90% of strains had minimum inhibitory concentrations of ≤32 mg/L. The urine-specific...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-06-01
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| Series: | Journal of Microbiology, Immunology and Infection |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1684118216300743 |
| _version_ | 1818411735166484480 |
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| author | Yun Li Bo Zheng Feng Xue Sai-Nan Zhu Yuan Lyu |
| author_facet | Yun Li Bo Zheng Feng Xue Sai-Nan Zhu Yuan Lyu |
| author_sort | Yun Li |
| collection | DOAJ |
| description | Eschrichia coli urinary isolates were collected from 20 Chinese hospitals during five 1-year periods from 2004 to 2014. The susceptibility of E. coli to levofloxacin has remained stable during the past 11 years, and 90% of strains had minimum inhibitory concentrations of ≤32 mg/L. The urine-specific susceptibility breakpoints for levofloxacin should be reset based on more relevant clinical studies and the current pharmacokinetic/pharmacodynamic considerations in this field. |
| first_indexed | 2024-12-14T10:36:08Z |
| format | Article |
| id | doaj.art-d3a130a1fd6543f09f2881e3c420fe2a |
| institution | Directory Open Access Journal |
| issn | 1684-1182 |
| language | English |
| last_indexed | 2024-12-14T10:36:08Z |
| publishDate | 2017-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Microbiology, Immunology and Infection |
| spelling | doaj.art-d3a130a1fd6543f09f2881e3c420fe2a2022-12-21T23:05:56ZengElsevierJournal of Microbiology, Immunology and Infection1684-11822017-06-0150339039210.1016/j.jmii.2016.06.009Changes in minimum inhibitory concentration of levofloxacin for Escherichia coli strains isolated from urine samples in mainland China, 2004 to 2014Yun Li0Bo Zheng1Feng Xue2Sai-Nan Zhu3Yuan Lyu4Institute of Clinical Pharmacology, Peking University First Hospital, Beijing 100034, ChinaInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing 100034, ChinaInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing 100034, ChinaDepartment of Biostatistics, Peking University First Hospital, Beijing 100034, ChinaInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing 100034, ChinaEschrichia coli urinary isolates were collected from 20 Chinese hospitals during five 1-year periods from 2004 to 2014. The susceptibility of E. coli to levofloxacin has remained stable during the past 11 years, and 90% of strains had minimum inhibitory concentrations of ≤32 mg/L. The urine-specific susceptibility breakpoints for levofloxacin should be reset based on more relevant clinical studies and the current pharmacokinetic/pharmacodynamic considerations in this field.http://www.sciencedirect.com/science/article/pii/S1684118216300743Escherichia colilevofloxacinsusceptibilityurinary tract infection |
| spellingShingle | Yun Li Bo Zheng Feng Xue Sai-Nan Zhu Yuan Lyu Changes in minimum inhibitory concentration of levofloxacin for Escherichia coli strains isolated from urine samples in mainland China, 2004 to 2014 Journal of Microbiology, Immunology and Infection Escherichia coli levofloxacin susceptibility urinary tract infection |
| title | Changes in minimum inhibitory concentration of levofloxacin for Escherichia coli strains isolated from urine samples in mainland China, 2004 to 2014 |
| title_full | Changes in minimum inhibitory concentration of levofloxacin for Escherichia coli strains isolated from urine samples in mainland China, 2004 to 2014 |
| title_fullStr | Changes in minimum inhibitory concentration of levofloxacin for Escherichia coli strains isolated from urine samples in mainland China, 2004 to 2014 |
| title_full_unstemmed | Changes in minimum inhibitory concentration of levofloxacin for Escherichia coli strains isolated from urine samples in mainland China, 2004 to 2014 |
| title_short | Changes in minimum inhibitory concentration of levofloxacin for Escherichia coli strains isolated from urine samples in mainland China, 2004 to 2014 |
| title_sort | changes in minimum inhibitory concentration of levofloxacin for escherichia coli strains isolated from urine samples in mainland china 2004 to 2014 |
| topic | Escherichia coli levofloxacin susceptibility urinary tract infection |
| url | http://www.sciencedirect.com/science/article/pii/S1684118216300743 |
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