Platelets enhance CD4+ central memory T cell responses via platelet factor 4-dependent mitochondrial biogenesis and cell proliferation

Platelets enhance CD4+ central memory T cell responses via platelet factor 4-dependent mitochondrial biogenesis and cell proliferation

Platelets regulate multiple aspects of CD4+ T cell immunity, and may exert distinct regulations among different T cell subsets. Our aim was to investigate how platelets regulate CD4+ central memory T cell (Tcm) responses. αCD3/αCD28-stimulated human CD4+ Tcm cells were cultured without or with plate...

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Bibliographic Details
Main Authors: Shuai Tan, Junhao Zhang, Yang Sun, Anton Gisterå, Zi Sheng, Rickard E. Malmström, Ming Hou, Jun Peng, Chunhong Ma, Wangjun Liao, Nailin Li
Format: Article
Language:English
Published: Taylor & Francis Group 2022-04-01
Series:Platelets
Subjects:
blood platelets
cd4-positive t central memory cells
cxcr3 receptor
mitochondria
platelet factor 4
Online Access:http://dx.doi.org/10.1080/09537104.2021.1936479

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