Synthesis, structure and antibacterial properties of a mononuclear Ag(I) complex, [Ag(OBz)(PTA)2] (OBz = benzoate, PTA = 1, 3, 5-triaza-7-phospadamantane)

Synthesis, structure and antibacterial properties of a mononuclear Ag(I) complex, [Ag(OBz)(PTA)2] (OBz = benzoate, PTA = 1, 3, 5-triaza-7-phospadamantane)

A new silver complex, namely [Ag(OBz)(PTA)2] (where OBz = benzoate and PTA = 1, 3, 5-triazaphospadamantane) has been synthesized and structurally characterized. The silver center resides in a triangular coordination environment, noticeably deviated from the plane defined by three ligands. [Ag(OBz)(P...

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Bibliographic Details
Main Authors: Arman Hasan, Despoina Varna, Indranil Chakraborty, Panagiotis A. Angaridis, Raphael G. Raptis
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Results in Chemistry
Subjects:
Silver complex
X-ray structure
Antibacterial agent
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715622002995
Description
Summary:A new silver complex, namely [Ag(OBz)(PTA)2] (where OBz = benzoate and PTA = 1, 3, 5-triazaphospadamantane) has been synthesized and structurally characterized. The silver center resides in a triangular coordination environment, noticeably deviated from the plane defined by three ligands. [Ag(OBz)(PTA)2] has excellent aqueous solubility and also moderate solubility in organic media. Antibacterial studies indicated the effectiveness of this complex towards growth inhibition of three nosocomial pathogens, namely, B. cereus, S. aureus and P aeruginosa. The MIC and IC50 values clearly suggested that the complex induced more significant antibacterial activity against the Gram (+) strains compared to the Gram (−) variety.
ISSN:2211-7156

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