Synthesis, structure and antibacterial properties of a mononuclear Ag(I) complex, [Ag(OBz)(PTA)2] (OBz = benzoate, PTA = 1, 3, 5-triaza-7-phospadamantane)
A new silver complex, namely [Ag(OBz)(PTA)2] (where OBz = benzoate and PTA = 1, 3, 5-triazaphospadamantane) has been synthesized and structurally characterized. The silver center resides in a triangular coordination environment, noticeably deviated from the plane defined by three ligands. [Ag(OBz)(P...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-01-01
|
| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715622002995 |
| _version_ | 1811178082034253824 |
|---|---|
| author | Arman Hasan Despoina Varna Indranil Chakraborty Panagiotis A. Angaridis Raphael G. Raptis |
| author_facet | Arman Hasan Despoina Varna Indranil Chakraborty Panagiotis A. Angaridis Raphael G. Raptis |
| author_sort | Arman Hasan |
| collection | DOAJ |
| description | A new silver complex, namely [Ag(OBz)(PTA)2] (where OBz = benzoate and PTA = 1, 3, 5-triazaphospadamantane) has been synthesized and structurally characterized. The silver center resides in a triangular coordination environment, noticeably deviated from the plane defined by three ligands. [Ag(OBz)(PTA)2] has excellent aqueous solubility and also moderate solubility in organic media. Antibacterial studies indicated the effectiveness of this complex towards growth inhibition of three nosocomial pathogens, namely, B. cereus, S. aureus and P aeruginosa. The MIC and IC50 values clearly suggested that the complex induced more significant antibacterial activity against the Gram (+) strains compared to the Gram (−) variety. |
| first_indexed | 2024-04-11T06:13:28Z |
| format | Article |
| id | doaj.art-d3a667ef67024da394f41f6e33700024 |
| institution | Directory Open Access Journal |
| issn | 2211-7156 |
| language | English |
| last_indexed | 2024-04-11T06:13:28Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj.art-d3a667ef67024da394f41f6e337000242022-12-22T04:41:09ZengElsevierResults in Chemistry2211-71562022-01-014100580Synthesis, structure and antibacterial properties of a mononuclear Ag(I) complex, [Ag(OBz)(PTA)2] (OBz = benzoate, PTA = 1, 3, 5-triaza-7-phospadamantane)Arman Hasan0Despoina Varna1Indranil Chakraborty2Panagiotis A. Angaridis3Raphael G. Raptis4Department of Chemistry & Biochemistry and the Biomolecular Sciences Institute, Florida International University, Miami, FL 33199, USALaboratory of Inorganic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, GreeceDepartment of Chemistry & Biochemistry and the Biomolecular Sciences Institute, Florida International University, Miami, FL 33199, USA; Corresponding author.Laboratory of Inorganic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, GreeceDepartment of Chemistry & Biochemistry and the Biomolecular Sciences Institute, Florida International University, Miami, FL 33199, USAA new silver complex, namely [Ag(OBz)(PTA)2] (where OBz = benzoate and PTA = 1, 3, 5-triazaphospadamantane) has been synthesized and structurally characterized. The silver center resides in a triangular coordination environment, noticeably deviated from the plane defined by three ligands. [Ag(OBz)(PTA)2] has excellent aqueous solubility and also moderate solubility in organic media. Antibacterial studies indicated the effectiveness of this complex towards growth inhibition of three nosocomial pathogens, namely, B. cereus, S. aureus and P aeruginosa. The MIC and IC50 values clearly suggested that the complex induced more significant antibacterial activity against the Gram (+) strains compared to the Gram (−) variety.http://www.sciencedirect.com/science/article/pii/S2211715622002995Silver complexX-ray structureAntibacterial agent |
| spellingShingle | Arman Hasan Despoina Varna Indranil Chakraborty Panagiotis A. Angaridis Raphael G. Raptis Synthesis, structure and antibacterial properties of a mononuclear Ag(I) complex, [Ag(OBz)(PTA)2] (OBz = benzoate, PTA = 1, 3, 5-triaza-7-phospadamantane) Results in Chemistry Silver complex X-ray structure Antibacterial agent |
| title | Synthesis, structure and antibacterial properties of a mononuclear Ag(I) complex, [Ag(OBz)(PTA)2] (OBz = benzoate, PTA = 1, 3, 5-triaza-7-phospadamantane) |
| title_full | Synthesis, structure and antibacterial properties of a mononuclear Ag(I) complex, [Ag(OBz)(PTA)2] (OBz = benzoate, PTA = 1, 3, 5-triaza-7-phospadamantane) |
| title_fullStr | Synthesis, structure and antibacterial properties of a mononuclear Ag(I) complex, [Ag(OBz)(PTA)2] (OBz = benzoate, PTA = 1, 3, 5-triaza-7-phospadamantane) |
| title_full_unstemmed | Synthesis, structure and antibacterial properties of a mononuclear Ag(I) complex, [Ag(OBz)(PTA)2] (OBz = benzoate, PTA = 1, 3, 5-triaza-7-phospadamantane) |
| title_short | Synthesis, structure and antibacterial properties of a mononuclear Ag(I) complex, [Ag(OBz)(PTA)2] (OBz = benzoate, PTA = 1, 3, 5-triaza-7-phospadamantane) |
| title_sort | synthesis structure and antibacterial properties of a mononuclear ag i complex ag obz pta 2 obz benzoate pta 1 3 5 triaza 7 phospadamantane |
| topic | Silver complex X-ray structure Antibacterial agent |
| url | http://www.sciencedirect.com/science/article/pii/S2211715622002995 |
| work_keys_str_mv | AT armanhasan synthesisstructureandantibacterialpropertiesofamononuclearagicomplexagobzpta2obzbenzoatepta135triaza7phospadamantane AT despoinavarna synthesisstructureandantibacterialpropertiesofamononuclearagicomplexagobzpta2obzbenzoatepta135triaza7phospadamantane AT indranilchakraborty synthesisstructureandantibacterialpropertiesofamononuclearagicomplexagobzpta2obzbenzoatepta135triaza7phospadamantane AT panagiotisaangaridis synthesisstructureandantibacterialpropertiesofamononuclearagicomplexagobzpta2obzbenzoatepta135triaza7phospadamantane AT raphaelgraptis synthesisstructureandantibacterialpropertiesofamononuclearagicomplexagobzpta2obzbenzoatepta135triaza7phospadamantane |