Cerebral Amyloid Angiopathy: A Case Report and Literature ...
Cerebral amyloid angiopathy (CAA) is a condition characterized by accumulation of amyloid-beta peptide in the walls of the small and medium-sized arteries of the brain and leptomeninges. This condition disrupts the structure of the vessel wall and makes it prone to bleeding. This is an important cau...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2015-03-01
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| Series: | Haseki Tıp Bülteni |
| Subjects: | |
| Online Access: | http://cms.galenos.com.tr/FileIssue/3/791/article/92-94.pdf |
| _version_ | 1797905850635911168 |
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| author | Orkide Kutlu Şamil Ecirli Serhat Aygün İbrahim Ünsal Muharrem Keskin Abdullah Sakin Abdulkadir Baştürk |
| author_facet | Orkide Kutlu Şamil Ecirli Serhat Aygün İbrahim Ünsal Muharrem Keskin Abdullah Sakin Abdulkadir Baştürk |
| author_sort | Orkide Kutlu |
| collection | DOAJ |
| description | Cerebral amyloid angiopathy (CAA) is a condition characterized by accumulation of amyloid-beta peptide in the walls of the small and medium-sized arteries of the brain and leptomeninges. This condition disrupts the structure of the vessel wall and makes it prone to bleeding. This is an important cause of intracerebral hemorrhage in elderly accompanying to Alzheimer’s disease or to a familial syndrome. Clinically, it usually presents with spontaneous lobar hemorrhage, as well as transient neurological signs, seizures, cognitive disorders, headache, incidental findings like microhaemorrhages and hemosiderosis observed on magnetic resonance (MR) imaging. Herein, we report a hypertensive patient diagnosed with CAA who presented with the complaints of balance disorder while walking. CAA should be suspected in patients with lobar hemorrhage aged 65 years and over. Surgical treatment should not be performed because it could worsen the condition. Clinical improvement can be expected from supportive management, monitoring hypertension, and steroid - immunosuppressive therapies. |
| first_indexed | 2024-04-10T10:11:41Z |
| format | Article |
| id | doaj.art-d3a6d427ee35468893e9133a0db05f96 |
| institution | Directory Open Access Journal |
| issn | 1302-0072 2147-2688 |
| language | English |
| last_indexed | 2024-04-10T10:11:41Z |
| publishDate | 2015-03-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Haseki Tıp Bülteni |
| spelling | doaj.art-d3a6d427ee35468893e9133a0db05f962023-02-15T16:22:06ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882015-03-01531929410.4274/haseki.2006Cerebral Amyloid Angiopathy: A Case Report and Literature ...Orkide Kutlu0Şamil Ecirli1Serhat Aygün2İbrahim Ünsal3Muharrem Keskin4Abdullah Sakin5Abdulkadir Baştürk6Konya Eğitim ve Araştırma Hastanesi, Dahiliye Kliniği, Konya, TürkiyeKonya Eğitim ve Araştırma Hastanesi, Dahiliye Kliniği, Konya, TürkiyeKonya Eğitim ve Araştırma Hastanesi, Radyoloji Kliniği, Konya, TürkiyeKonya Eğitim ve Araştırma Hastanesi, Nöroloji Kliniği, Konya, TürkiyeKonya Eğitim ve Araştırma Hastanesi, Dahiliye Kliniği, Konya, TürkiyeKanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi, Dahiliye Kliniği, İstanbul, TürkiyeKonya Eğitim ve Araştırma Hastanesi, Dahiliye Kliniği, Konya, TürkiyeCerebral amyloid angiopathy (CAA) is a condition characterized by accumulation of amyloid-beta peptide in the walls of the small and medium-sized arteries of the brain and leptomeninges. This condition disrupts the structure of the vessel wall and makes it prone to bleeding. This is an important cause of intracerebral hemorrhage in elderly accompanying to Alzheimer’s disease or to a familial syndrome. Clinically, it usually presents with spontaneous lobar hemorrhage, as well as transient neurological signs, seizures, cognitive disorders, headache, incidental findings like microhaemorrhages and hemosiderosis observed on magnetic resonance (MR) imaging. Herein, we report a hypertensive patient diagnosed with CAA who presented with the complaints of balance disorder while walking. CAA should be suspected in patients with lobar hemorrhage aged 65 years and over. Surgical treatment should not be performed because it could worsen the condition. Clinical improvement can be expected from supportive management, monitoring hypertension, and steroid - immunosuppressive therapies.http://cms.galenos.com.tr/FileIssue/3/791/article/92-94.pdfintracerebral hemorrhagehypertensionCerebral amyloid angiopathyhypertension |
| spellingShingle | Orkide Kutlu Şamil Ecirli Serhat Aygün İbrahim Ünsal Muharrem Keskin Abdullah Sakin Abdulkadir Baştürk Cerebral Amyloid Angiopathy: A Case Report and Literature ... Haseki Tıp Bülteni intracerebral hemorrhage hypertension Cerebral amyloid angiopathy hypertension |
| title | Cerebral Amyloid Angiopathy: A Case Report and Literature ... |
| title_full | Cerebral Amyloid Angiopathy: A Case Report and Literature ... |
| title_fullStr | Cerebral Amyloid Angiopathy: A Case Report and Literature ... |
| title_full_unstemmed | Cerebral Amyloid Angiopathy: A Case Report and Literature ... |
| title_short | Cerebral Amyloid Angiopathy: A Case Report and Literature ... |
| title_sort | cerebral amyloid angiopathy a case report and literature |
| topic | intracerebral hemorrhage hypertension Cerebral amyloid angiopathy hypertension |
| url | http://cms.galenos.com.tr/FileIssue/3/791/article/92-94.pdf |
| work_keys_str_mv | AT orkidekutlu cerebralamyloidangiopathyacasereportandliterature AT samilecirli cerebralamyloidangiopathyacasereportandliterature AT serhataygun cerebralamyloidangiopathyacasereportandliterature AT ibrahimunsal cerebralamyloidangiopathyacasereportandliterature AT muharremkeskin cerebralamyloidangiopathyacasereportandliterature AT abdullahsakin cerebralamyloidangiopathyacasereportandliterature AT abdulkadirbasturk cerebralamyloidangiopathyacasereportandliterature |