Brief research report: Effects of Pinch deficiency on cartilage homeostasis in adult mice

Brief research report: Effects of Pinch deficiency on cartilage homeostasis in adult mice

Pinch1 and Pinch2 are LIM domain-containing proteins with crucial functions in mediating focal adhesion formation. Our previous studies have demonstrated that Pinch1/2 expression is essential for cartilage and bone formation during skeletal development in mice. Loss of Pinch expression (Prx1Cre; Pin...

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Bibliographic Details
Main Authors: Xiaohao Wu, Sixiong Lin, Rongdong Liao, Qing Yao, Lijun Lin, Xuenong Zou, Guozhi Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Pinch
focal adhesion
articular cartilage
osteoarthritis
homeostasis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1116128/full

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