Pre-hospital pulse glucocorticoid therapy in patients with ST-segment elevation myocardial infarction transferred for primary percutaneous coronary intervention: a randomized controlled trial (PULSE-MI)

Pre-hospital pulse glucocorticoid therapy in patients with ST-segment elevation myocardial infarction transferred for primary percutaneous coronary intervention: a randomized controlled trial (PULSE-MI)

Abstract Background Inflammation in ST-segment elevation myocardial infarction (STEMI) is an important contributor to both acute myocardial ischemia and reperfusion injury after primary percutaneous coronary intervention (PCI). Methylprednisolone is a glucocorticoid with potent anti-inflammatory pro...

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Bibliographic Details
Main Authors: Jasmine Melissa Madsen, Laust Emil Roelsgaard Obling, Laura Rytoft, Fredrik Folke, Christian Hassager, Lars Bredevang Andersen, Niels Vejlstrup, Lia Evi Bang, Thomas Engstrøm, Jacob Thomsen Lønborg
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Trials
Subjects:
ST-segment elevation myocardial infarction
Pre-hospital intervention
Randomized controlled trials
Inflammation
Reperfusion Injury
Steroid
Online Access:https://doi.org/10.1186/s13063-023-07830-y

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