The Role of Post-Translational Modifications in Regulation of NLRP3 Inflammasome Activation

The Role of Post-Translational Modifications in Regulation of NLRP3 Inflammasome Activation

Pathogen-associated molecular patterns (PAMPs) and danger-associated molecular patterns (DAMPs) induce NLRP3 inflammasome activation, and subsequent formation of active caspase-1 as well as the maturation of interleukin-1β (IL-1β) and gasdermin D (GSDMD), mediating the occurrence of pyroptosis and i...

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Bibliographic Details
Main Authors: Jing Xia, Songhong Jiang, Shiqi Dong, Yonghong Liao, Yang Zhou
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
inflammasome
NLRP3
post-translational modification
Online Access:https://www.mdpi.com/1422-0067/24/7/6126

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