Probabilistic atlases of default mode, executive control and salience network white matter tracts: An fMRI-guided diffusion tensor imaging and tractography study
Diffusion tensor imaging (DTI) is a powerful MRI technique that can be used to estimate both the microstructural integrity and the trajectories of white matter pathways throughout the central nervous system. This fiber tracking (aka, tractography) approach is often carried out using anatomically-de...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2015-11-01
|
| Series: | Frontiers in Human Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnhum.2015.00585/full |
| _version_ | 1818874513463443456 |
|---|---|
| author | Teresa D. Figley Teresa D. Figley Navdeep eBhullar Navdeep eBhullar Susan M. Courtney Susan M. Courtney Susan M. Courtney Chase R. Figley Chase R. Figley Chase R. Figley |
| author_facet | Teresa D. Figley Teresa D. Figley Navdeep eBhullar Navdeep eBhullar Susan M. Courtney Susan M. Courtney Susan M. Courtney Chase R. Figley Chase R. Figley Chase R. Figley |
| author_sort | Teresa D. Figley |
| collection | DOAJ |
| description | Diffusion tensor imaging (DTI) is a powerful MRI technique that can be used to estimate both the microstructural integrity and the trajectories of white matter pathways throughout the central nervous system. This fiber tracking (aka, tractography) approach is often carried out using anatomically-defined seed points to identify white matter tracts that pass through one or more structures, but can also be performed using functionally-defined regions of interest (ROIs) that have been determined using functional MRI (fMRI) or other methods. In this study, we performed fMRI-guided DTI tractography between all of the previously defined nodes within each of six common resting-state brain networks, including the: dorsal Default Mode Network (dDMN), ventral Default Mode Network (vDMN), left Executive Control Network (lECN), right Executive Control Network (rECN), anterior Salience Network (aSN), and posterior Salience Network (pSN). By normalizing the data from 32 healthy control subjects to a standard template – using high-dimensional, non-linear warping methods – we were able to create probabilistic white matter atlases for each tract in stereotaxic coordinates. By investigating all 198 ROI-to-ROI combinations within the aforementioned resting-state networks (for a total of 6336 independent DTI tractography analyses), the resulting probabilistic atlases represent a comprehensive cohort of functionally-defined white matter regions that can be used in future brain imaging studies to: 1) ascribe DTI or other white matter changes to particular functional brain networks, and 2) compliment resting state fMRI or other functional connectivity analyses. |
| first_indexed | 2024-12-19T13:11:48Z |
| format | Article |
| id | doaj.art-d3adc5b513634a8fbc179971f589a093 |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-12-19T13:11:48Z |
| publishDate | 2015-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-d3adc5b513634a8fbc179971f589a0932022-12-21T20:19:55ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612015-11-01910.3389/fnhum.2015.00585158796Probabilistic atlases of default mode, executive control and salience network white matter tracts: An fMRI-guided diffusion tensor imaging and tractography studyTeresa D. Figley0Teresa D. Figley1Navdeep eBhullar2Navdeep eBhullar3Susan M. Courtney4Susan M. Courtney5Susan M. Courtney6Chase R. Figley7Chase R. Figley8Chase R. Figley9University of ManitobaKleysen Institute for Advanced Medicine, Winnipeg Health Sciences CentreUniversity of ManitobaKleysen Institute for Advanced Medicine, Winnipeg Health Sciences CentreJohns Hopkins UniversityJohns Hopkins UniversityKennedy Krieger InstituteUniversity of ManitobaKleysen Institute for Advanced Medicine, Winnipeg Health Sciences CentreJohns Hopkins UniversityDiffusion tensor imaging (DTI) is a powerful MRI technique that can be used to estimate both the microstructural integrity and the trajectories of white matter pathways throughout the central nervous system. This fiber tracking (aka, tractography) approach is often carried out using anatomically-defined seed points to identify white matter tracts that pass through one or more structures, but can also be performed using functionally-defined regions of interest (ROIs) that have been determined using functional MRI (fMRI) or other methods. In this study, we performed fMRI-guided DTI tractography between all of the previously defined nodes within each of six common resting-state brain networks, including the: dorsal Default Mode Network (dDMN), ventral Default Mode Network (vDMN), left Executive Control Network (lECN), right Executive Control Network (rECN), anterior Salience Network (aSN), and posterior Salience Network (pSN). By normalizing the data from 32 healthy control subjects to a standard template – using high-dimensional, non-linear warping methods – we were able to create probabilistic white matter atlases for each tract in stereotaxic coordinates. By investigating all 198 ROI-to-ROI combinations within the aforementioned resting-state networks (for a total of 6336 independent DTI tractography analyses), the resulting probabilistic atlases represent a comprehensive cohort of functionally-defined white matter regions that can be used in future brain imaging studies to: 1) ascribe DTI or other white matter changes to particular functional brain networks, and 2) compliment resting state fMRI or other functional connectivity analyses.http://journal.frontiersin.org/Journal/10.3389/fnhum.2015.00585/fullBrain MappingconnectivityDTIexecutive controlfMRInetwork |
| spellingShingle | Teresa D. Figley Teresa D. Figley Navdeep eBhullar Navdeep eBhullar Susan M. Courtney Susan M. Courtney Susan M. Courtney Chase R. Figley Chase R. Figley Chase R. Figley Probabilistic atlases of default mode, executive control and salience network white matter tracts: An fMRI-guided diffusion tensor imaging and tractography study Frontiers in Human Neuroscience Brain Mapping connectivity DTI executive control fMRI network |
| title | Probabilistic atlases of default mode, executive control and salience network white matter tracts: An fMRI-guided diffusion tensor imaging and tractography study |
| title_full | Probabilistic atlases of default mode, executive control and salience network white matter tracts: An fMRI-guided diffusion tensor imaging and tractography study |
| title_fullStr | Probabilistic atlases of default mode, executive control and salience network white matter tracts: An fMRI-guided diffusion tensor imaging and tractography study |
| title_full_unstemmed | Probabilistic atlases of default mode, executive control and salience network white matter tracts: An fMRI-guided diffusion tensor imaging and tractography study |
| title_short | Probabilistic atlases of default mode, executive control and salience network white matter tracts: An fMRI-guided diffusion tensor imaging and tractography study |
| title_sort | probabilistic atlases of default mode executive control and salience network white matter tracts an fmri guided diffusion tensor imaging and tractography study |
| topic | Brain Mapping connectivity DTI executive control fMRI network |
| url | http://journal.frontiersin.org/Journal/10.3389/fnhum.2015.00585/full |
| work_keys_str_mv | AT teresadfigley probabilisticatlasesofdefaultmodeexecutivecontrolandsaliencenetworkwhitemattertractsanfmriguideddiffusiontensorimagingandtractographystudy AT teresadfigley probabilisticatlasesofdefaultmodeexecutivecontrolandsaliencenetworkwhitemattertractsanfmriguideddiffusiontensorimagingandtractographystudy AT navdeepebhullar probabilisticatlasesofdefaultmodeexecutivecontrolandsaliencenetworkwhitemattertractsanfmriguideddiffusiontensorimagingandtractographystudy AT navdeepebhullar probabilisticatlasesofdefaultmodeexecutivecontrolandsaliencenetworkwhitemattertractsanfmriguideddiffusiontensorimagingandtractographystudy AT susanmcourtney probabilisticatlasesofdefaultmodeexecutivecontrolandsaliencenetworkwhitemattertractsanfmriguideddiffusiontensorimagingandtractographystudy AT susanmcourtney probabilisticatlasesofdefaultmodeexecutivecontrolandsaliencenetworkwhitemattertractsanfmriguideddiffusiontensorimagingandtractographystudy AT susanmcourtney probabilisticatlasesofdefaultmodeexecutivecontrolandsaliencenetworkwhitemattertractsanfmriguideddiffusiontensorimagingandtractographystudy AT chaserfigley probabilisticatlasesofdefaultmodeexecutivecontrolandsaliencenetworkwhitemattertractsanfmriguideddiffusiontensorimagingandtractographystudy AT chaserfigley probabilisticatlasesofdefaultmodeexecutivecontrolandsaliencenetworkwhitemattertractsanfmriguideddiffusiontensorimagingandtractographystudy AT chaserfigley probabilisticatlasesofdefaultmodeexecutivecontrolandsaliencenetworkwhitemattertractsanfmriguideddiffusiontensorimagingandtractographystudy |