Accumulation of alpha-synuclein within the liver, potential role in the clearance of brain pathology associated with Parkinson’s disease
Abstract Alpha-synuclein (α-syn) aggregation is the hallmark pathological lesion in brains of patients with Parkinson’s disease (PD) and related neurological disorders characterized as synucleinopathies. Accumulating evidence now indicates that α-syn deposition is also present within the gut and oth...
Main Authors: | Juan F. Reyes, Sara Ekmark-Léwen, Marina Perdiki, Therése Klingstedt, Alana Hoffmann, Emilia Wiechec, Per Nilsson, K. Peter R. Nilsson, Irina Alafuzoff, Martin Ingelsson, Martin Hallbeck |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
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Series: | Acta Neuropathologica Communications |
Online Access: | https://doi.org/10.1186/s40478-021-01136-3 |
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