Proteomic characterization of the Toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and function
The basal complex is orchestrating Toxoplasma gondii cell division steps. Here, the authors use proximity biotinylation to map the proteome of this contractile ring, identify components acting on its formation, stability and constriction, and reveal bidirectional daughter budding.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-32151-0 |
| _version_ | 1798042484081688576 |
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| author | Klemens Engelberg Tyler Bechtel Cynthia Michaud Eranthie Weerapana Marc-Jan Gubbels |
| author_facet | Klemens Engelberg Tyler Bechtel Cynthia Michaud Eranthie Weerapana Marc-Jan Gubbels |
| author_sort | Klemens Engelberg |
| collection | DOAJ |
| description | The basal complex is orchestrating Toxoplasma gondii cell division steps. Here, the authors use proximity biotinylation to map the proteome of this contractile ring, identify components acting on its formation, stability and constriction, and reveal bidirectional daughter budding. |
| first_indexed | 2024-04-11T22:36:09Z |
| format | Article |
| id | doaj.art-d3b4f87b674541269826837f27722ecd |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T22:36:09Z |
| publishDate | 2022-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-d3b4f87b674541269826837f27722ecd2022-12-22T03:59:13ZengNature PortfolioNature Communications2041-17232022-08-0113111510.1038/s41467-022-32151-0Proteomic characterization of the Toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and functionKlemens Engelberg0Tyler Bechtel1Cynthia Michaud2Eranthie Weerapana3Marc-Jan Gubbels4Department of Biology, Boston CollegeDepartment of Chemistry, Boston CollegeDepartment of Biology, Boston CollegeDepartment of Chemistry, Boston CollegeDepartment of Biology, Boston CollegeThe basal complex is orchestrating Toxoplasma gondii cell division steps. Here, the authors use proximity biotinylation to map the proteome of this contractile ring, identify components acting on its formation, stability and constriction, and reveal bidirectional daughter budding.https://doi.org/10.1038/s41467-022-32151-0 |
| spellingShingle | Klemens Engelberg Tyler Bechtel Cynthia Michaud Eranthie Weerapana Marc-Jan Gubbels Proteomic characterization of the Toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and function Nature Communications |
| title | Proteomic characterization of the Toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and function |
| title_full | Proteomic characterization of the Toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and function |
| title_fullStr | Proteomic characterization of the Toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and function |
| title_full_unstemmed | Proteomic characterization of the Toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and function |
| title_short | Proteomic characterization of the Toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and function |
| title_sort | proteomic characterization of the toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and function |
| url | https://doi.org/10.1038/s41467-022-32151-0 |
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