Sirtuins and Insulin Resistance

Sirtuins and Insulin Resistance

The mammalian Sirtuins (SIRT1-7) are an evolutionarily conserved family of NAD+-dependent deacylase and mono-ADP-ribosyltransferase. Sirtuins display distinct subcellular localizations and functions and are involved in cell survival, senescence, metabolism and genome stability. Among the mammalian S...

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Bibliographic Details
Main Authors: Shuang Zhou, Xiaoqiang Tang, Hou-Zao Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Endocrinology
Subjects:
sirtuins
insulin resistance
senescaging
inflammation
mitochondrial dysfunction
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00748/full

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