Sensitivity of the Natriuretic Peptide/cGMP System to Hyperammonaemia in Rat C6 Glioma Cells and GPNT Brain Endothelial Cells

Sensitivity of the Natriuretic Peptide/cGMP System to Hyperammonaemia in Rat C6 Glioma Cells and GPNT Brain Endothelial Cells

C-type natriuretic peptide (CNP) is the major natriuretic peptide of the central nervous system and acts via its selective guanylyl cyclase-B (GC-B) receptor to regulate cGMP production in neurons, astrocytes and endothelial cells. CNP is implicated in the regulation of neurogenesis, axonal bifurcat...

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Bibliographic Details
Main Authors: Jacob T. Regan, Samantha M. Mirczuk, Christopher J. Scudder, Emily Stacey, Sabah Khan, Michael Worwood, Torinn Powles, J. Sebastian Dennis-Beron, Matthew Ginley-Hidinger, Imelda M. McGonnell, Holger A. Volk, Rhiannon Strickland, Michael S. Tivers, Charlotte Lawson, Victoria J. Lipscomb, Robert C. Fowkes
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
natriuretic peptides
cGMP
hyperammonaemia
astrocyte
neuroendocrinology
endothelial cells
Online Access:https://www.mdpi.com/2073-4409/10/2/398

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