Dramatic increase in volume versus length of invasive ductal carcinoma mimicking intramammary lymph node in a small nodular lesion
Abstract Background The tumor growth pattern in breast cancer appears to be variable and unpredictable. A minor increase in size in a pre-existing lesion, especially under 1 cm, corresponds to a more pronounced increase in volume. Case presentation We report a 63-year-old woman with a nodular densit...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-05-01
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| Series: | Bulletin of the National Research Centre |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s42269-022-00823-y |
| _version_ | 1818005820850307072 |
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| author | Seda Aladag Kurt Varol Celik |
| author_facet | Seda Aladag Kurt Varol Celik |
| author_sort | Seda Aladag Kurt |
| collection | DOAJ |
| description | Abstract Background The tumor growth pattern in breast cancer appears to be variable and unpredictable. A minor increase in size in a pre-existing lesion, especially under 1 cm, corresponds to a more pronounced increase in volume. Case presentation We report a 63-year-old woman with a nodular density mimicking intramammary lymph node, diagnosed as invasive carcinoma of luminal B subtype. The lesion increased size and density over time in following mammograms until having indistinct margins. While the tumor volume was 12.7 mm3 at the first observation on mammography, it has increased approximately 6.7 times to reach 85.7 mm3 in four years. Finally, the patient diagnosed with early-stage breast cancer (T1N0M0) was treated with breast-conserving surgery. Conclusions Minor changes in size, density, and margin status of a lesion on serial mammograms are warning for breast cancer. Withal, a slight increase in lesion size in two dimensions can result in significant differences in volume. Therefore, comparative evaluation with previous mammograms and observing any difference in morphological features by screening are crucial for early diagnosis and optimal management of the disease. |
| first_indexed | 2024-04-14T04:50:32Z |
| format | Article |
| id | doaj.art-d3b62ab8efa0492bbf2638a6b4d72550 |
| institution | Directory Open Access Journal |
| issn | 2522-8307 |
| language | English |
| last_indexed | 2024-04-14T04:50:32Z |
| publishDate | 2022-05-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Bulletin of the National Research Centre |
| spelling | doaj.art-d3b62ab8efa0492bbf2638a6b4d725502022-12-22T02:11:19ZengSpringerOpenBulletin of the National Research Centre2522-83072022-05-014611510.1186/s42269-022-00823-yDramatic increase in volume versus length of invasive ductal carcinoma mimicking intramammary lymph node in a small nodular lesionSeda Aladag Kurt0Varol Celik1Department of Radiology, Cerrahpasa Faculty of Medicine, Istanbul University-CerrahpasaDepartment of General Surgery, Cerrahpasa Faculty of Medicine, Istanbul University-CerrahpasaAbstract Background The tumor growth pattern in breast cancer appears to be variable and unpredictable. A minor increase in size in a pre-existing lesion, especially under 1 cm, corresponds to a more pronounced increase in volume. Case presentation We report a 63-year-old woman with a nodular density mimicking intramammary lymph node, diagnosed as invasive carcinoma of luminal B subtype. The lesion increased size and density over time in following mammograms until having indistinct margins. While the tumor volume was 12.7 mm3 at the first observation on mammography, it has increased approximately 6.7 times to reach 85.7 mm3 in four years. Finally, the patient diagnosed with early-stage breast cancer (T1N0M0) was treated with breast-conserving surgery. Conclusions Minor changes in size, density, and margin status of a lesion on serial mammograms are warning for breast cancer. Withal, a slight increase in lesion size in two dimensions can result in significant differences in volume. Therefore, comparative evaluation with previous mammograms and observing any difference in morphological features by screening are crucial for early diagnosis and optimal management of the disease.https://doi.org/10.1186/s42269-022-00823-yBreast cancerScreeningMammographyIntramammary lymph node3D |
| spellingShingle | Seda Aladag Kurt Varol Celik Dramatic increase in volume versus length of invasive ductal carcinoma mimicking intramammary lymph node in a small nodular lesion Bulletin of the National Research Centre Breast cancer Screening Mammography Intramammary lymph node 3D |
| title | Dramatic increase in volume versus length of invasive ductal carcinoma mimicking intramammary lymph node in a small nodular lesion |
| title_full | Dramatic increase in volume versus length of invasive ductal carcinoma mimicking intramammary lymph node in a small nodular lesion |
| title_fullStr | Dramatic increase in volume versus length of invasive ductal carcinoma mimicking intramammary lymph node in a small nodular lesion |
| title_full_unstemmed | Dramatic increase in volume versus length of invasive ductal carcinoma mimicking intramammary lymph node in a small nodular lesion |
| title_short | Dramatic increase in volume versus length of invasive ductal carcinoma mimicking intramammary lymph node in a small nodular lesion |
| title_sort | dramatic increase in volume versus length of invasive ductal carcinoma mimicking intramammary lymph node in a small nodular lesion |
| topic | Breast cancer Screening Mammography Intramammary lymph node 3D |
| url | https://doi.org/10.1186/s42269-022-00823-y |
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