Dihydromyricetin ameliorates vascular endothelial damage by inhibiting NLRP3 inflammasome activity through Sirtuin 3
Objective To investigate the inhibitory effects and mechanism of dihydromyricetin (DHM) on the activation of NLRP3 inflammasome and improvement of palmitic acid induced injury in vascular endothelial cells through Sirtuin 3(Sirt3). Methods Human umbilical vein endothelial cells (HUVECs) were treated...
Main Authors: | LIU Minghua, SHEN Hui, WANG Xiaolan, ZHOU Xi, ZHANG Ting |
---|---|
Format: | Article |
Language: | zho |
Published: |
Editorial Office of Journal of Army Medical University
2023-05-01
|
Series: | 陆军军医大学学报 |
Subjects: | |
Online Access: | http://aammt.tmmu.edu.cn/html/202211043.htm |
Similar Items
-
Dihydromyricetin suppresses endothelial NLRP3 inflammasome activation and attenuates atherogenesis by promoting mitophagy
by: Qin Hu, et al.
Published: (2024-09-01) -
Protective effects of sirtuin 3 on titanium particle-induced osteogenic inhibition by regulating the NLRP3 inflammasome via the GSK-3β/β-catenin signalling pathway
by: Kai Zheng, et al.
Published: (2021-10-01) -
Autophagy in Atherosclerotic Plaque Cells: Targeting NLRP3 Inflammasome for Self-Rescue
by: Xuelian Li, et al.
Published: (2022-12-01) -
NLPR3 Inflammasomes and Their Significance for Atherosclerosis
by: Anastasia V. Poznyak, et al.
Published: (2020-07-01) -
The Role of Inflammasome-Dependent and Inflammasome-Independent NLRP3 in the Kidney
by: Yang Gyun Kim, et al.
Published: (2019-11-01)