Gastroduodenal Perforation in a Child With Sickle Cell Anemia: A Case Report

Objectives: Gastroduodenal perforation (GDP) is a rare cause of acute abdominal pain in children. Case Presentation: A 12-year-old boy presented with abdominal pain around the periumbilical and epigastric region on 7previous days. His familial history was significant for sickle cell anemia in the mo...

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Main Authors: Sanaz Mehrabani, Hassnan Mahmoodi Nesheli, Abbas Hadipur, Leila Moslemi
Format: Article
Language:English
Published: Aras Part Medical International Press 2023-04-01
Series:Crescent Journal of Medical and Biological Sciences
Subjects:
Online Access:http://www.cjmb.org/pdf.php?id=557
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author Sanaz Mehrabani
Hassnan Mahmoodi Nesheli
Abbas Hadipur
Leila Moslemi
author_facet Sanaz Mehrabani
Hassnan Mahmoodi Nesheli
Abbas Hadipur
Leila Moslemi
author_sort Sanaz Mehrabani
collection DOAJ
description Objectives: Gastroduodenal perforation (GDP) is a rare cause of acute abdominal pain in children. Case Presentation: A 12-year-old boy presented with abdominal pain around the periumbilical and epigastric region on 7previous days. His familial history was significant for sickle cell anemia in the mother and minor thalassemia in the father. He had been diagnosed with sickle cell anemia at the age of 4 years and had received blood transfusion and hydroxyurea every month. At physical examination, a distended abdomen and decreased intestinal sounds were seen. Also, he had a history of cholecystectomy (for cholelithiasis). Fecal occult blood was detected, while no Helicobacter pylori antigen was present. Abdominal ultrasound examination revealed splenomegaly and evidence of free fluid. Surgical results showed bile discharge in the abdominal cavity, and perforation of duodenum and pylorus. Conclusions: Since the symptoms of GDP in children are non-specific, especially in children with sickle cell anemia, it should be considered in these patients with abdominal pain.
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spelling doaj.art-d3bd41999be34020925ff7f9005974e42023-05-09T07:42:45ZengAras Part Medical International PressCrescent Journal of Medical and Biological Sciences2148-96962023-04-0110210510710.34172/cjmb.2023.16CJMB-9081Gastroduodenal Perforation in a Child With Sickle Cell Anemia: A Case ReportSanaz Mehrabani0Hassnan Mahmoodi Nesheli1Abbas Hadipur2Leila Moslemi3Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.Health Reproductive Research Center, Sari Branch, Islamic Azad University, Sari, Iran.Objectives: Gastroduodenal perforation (GDP) is a rare cause of acute abdominal pain in children. Case Presentation: A 12-year-old boy presented with abdominal pain around the periumbilical and epigastric region on 7previous days. His familial history was significant for sickle cell anemia in the mother and minor thalassemia in the father. He had been diagnosed with sickle cell anemia at the age of 4 years and had received blood transfusion and hydroxyurea every month. At physical examination, a distended abdomen and decreased intestinal sounds were seen. Also, he had a history of cholecystectomy (for cholelithiasis). Fecal occult blood was detected, while no Helicobacter pylori antigen was present. Abdominal ultrasound examination revealed splenomegaly and evidence of free fluid. Surgical results showed bile discharge in the abdominal cavity, and perforation of duodenum and pylorus. Conclusions: Since the symptoms of GDP in children are non-specific, especially in children with sickle cell anemia, it should be considered in these patients with abdominal pain.http://www.cjmb.org/pdf.php?id=557peptic ulceranemiasickle cellchild
spellingShingle Sanaz Mehrabani
Hassnan Mahmoodi Nesheli
Abbas Hadipur
Leila Moslemi
Gastroduodenal Perforation in a Child With Sickle Cell Anemia: A Case Report
Crescent Journal of Medical and Biological Sciences
peptic ulcer
anemia
sickle cell
child
title Gastroduodenal Perforation in a Child With Sickle Cell Anemia: A Case Report
title_full Gastroduodenal Perforation in a Child With Sickle Cell Anemia: A Case Report
title_fullStr Gastroduodenal Perforation in a Child With Sickle Cell Anemia: A Case Report
title_full_unstemmed Gastroduodenal Perforation in a Child With Sickle Cell Anemia: A Case Report
title_short Gastroduodenal Perforation in a Child With Sickle Cell Anemia: A Case Report
title_sort gastroduodenal perforation in a child with sickle cell anemia a case report
topic peptic ulcer
anemia
sickle cell
child
url http://www.cjmb.org/pdf.php?id=557
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AT abbashadipur gastroduodenalperforationinachildwithsicklecellanemiaacasereport
AT leilamoslemi gastroduodenalperforationinachildwithsicklecellanemiaacasereport