Role of nitric oxide in management of acute respiratory distress syndrome

The current mortality rate of patients suffering from acute respiratory distress syndrome (ARDS) is between 45% and 92%, with most dying within the first two weeks of the illness. In an effort to combat such an alarmingly high mortality rate, various treatment therapies such as...

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Bibliographic Details
Main Authors: Akmal A, Hasan Mohd
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2008-01-01
Series:Annals of Thoracic Medicine
Subjects:
Online Access:http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2008;volume=3;issue=3;spage=100;epage=103;aulast=Akmal
Description
Summary:The current mortality rate of patients suffering from acute respiratory distress syndrome (ARDS) is between 45% and 92%, with most dying within the first two weeks of the illness. In an effort to combat such an alarmingly high mortality rate, various treatment therapies such as low tidal volume ventilation strategies, corticosteroid therapy, and use of nitric oxide (NO) have been attempted in the management of patients with ARDS. Three cases which were admitted to the ICU and confirmed to have ARDS were unable to be weaned from ventilatory support, and nitric oxide therapy was initiated. It improved patients′ oxygenation for short periods of time but did not affect the mortality. The patients could not be weaned from the ventilator and expired.
ISSN:1817-1737
1998-3557