Role of nitric oxide in management of acute respiratory distress syndrome

The current mortality rate of patients suffering from acute respiratory distress syndrome (ARDS) is between 45% and 92%, with most dying within the first two weeks of the illness. In an effort to combat such an alarmingly high mortality rate, various treatment therapies such as...

Full description

Bibliographic Details
Main Authors: Akmal A, Hasan Mohd
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2008-01-01
Series:Annals of Thoracic Medicine
Subjects:
Online Access:http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2008;volume=3;issue=3;spage=100;epage=103;aulast=Akmal
_version_ 1819014683349221376
author Akmal A
Hasan Mohd
author_facet Akmal A
Hasan Mohd
author_sort Akmal A
collection DOAJ
description The current mortality rate of patients suffering from acute respiratory distress syndrome (ARDS) is between 45% and 92%, with most dying within the first two weeks of the illness. In an effort to combat such an alarmingly high mortality rate, various treatment therapies such as low tidal volume ventilation strategies, corticosteroid therapy, and use of nitric oxide (NO) have been attempted in the management of patients with ARDS. Three cases which were admitted to the ICU and confirmed to have ARDS were unable to be weaned from ventilatory support, and nitric oxide therapy was initiated. It improved patients′ oxygenation for short periods of time but did not affect the mortality. The patients could not be weaned from the ventilator and expired.
first_indexed 2024-12-21T02:19:44Z
format Article
id doaj.art-d3bd6bbb4fe74e1d872b811f3b8115bf
institution Directory Open Access Journal
issn 1817-1737
1998-3557
language English
last_indexed 2024-12-21T02:19:44Z
publishDate 2008-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Annals of Thoracic Medicine
spelling doaj.art-d3bd6bbb4fe74e1d872b811f3b8115bf2022-12-21T19:19:11ZengWolters Kluwer Medknow PublicationsAnnals of Thoracic Medicine1817-17371998-35572008-01-0133100103Role of nitric oxide in management of acute respiratory distress syndromeAkmal AHasan MohdThe current mortality rate of patients suffering from acute respiratory distress syndrome (ARDS) is between 45% and 92%, with most dying within the first two weeks of the illness. In an effort to combat such an alarmingly high mortality rate, various treatment therapies such as low tidal volume ventilation strategies, corticosteroid therapy, and use of nitric oxide (NO) have been attempted in the management of patients with ARDS. Three cases which were admitted to the ICU and confirmed to have ARDS were unable to be weaned from ventilatory support, and nitric oxide therapy was initiated. It improved patients′ oxygenation for short periods of time but did not affect the mortality. The patients could not be weaned from the ventilator and expired.http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2008;volume=3;issue=3;spage=100;epage=103;aulast=AkmalAcute respiratory distress syndromenitric oxidePACventilator
spellingShingle Akmal A
Hasan Mohd
Role of nitric oxide in management of acute respiratory distress syndrome
Annals of Thoracic Medicine
Acute respiratory distress syndrome
nitric oxide
PAC
ventilator
title Role of nitric oxide in management of acute respiratory distress syndrome
title_full Role of nitric oxide in management of acute respiratory distress syndrome
title_fullStr Role of nitric oxide in management of acute respiratory distress syndrome
title_full_unstemmed Role of nitric oxide in management of acute respiratory distress syndrome
title_short Role of nitric oxide in management of acute respiratory distress syndrome
title_sort role of nitric oxide in management of acute respiratory distress syndrome
topic Acute respiratory distress syndrome
nitric oxide
PAC
ventilator
url http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2008;volume=3;issue=3;spage=100;epage=103;aulast=Akmal
work_keys_str_mv AT akmala roleofnitricoxideinmanagementofacuterespiratorydistresssyndrome
AT hasanmohd roleofnitricoxideinmanagementofacuterespiratorydistresssyndrome