Evaluation of safety and efficacy of rapamycin-eluting balloon in patients with intracranial atherosclerotic stenosis: a cohort study
Abstract Objective The safety and efficacy of drug-eluting balloon on the treatment of intracranial atherosclerotic stenosis (ICAS) remain unclear. Here, we present our observation in a cohort study on the safety and efficacy of rapamycin-eluting balloon for patients with ICAS. Methods A total of 80...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-04-01
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| Series: | Journal of Cardiothoracic Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13019-023-02204-6 |
| _version_ | 1797836312804327424 |
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| author | Guodong Xu Xiaoli Dong Yingying Tian Liang Ma Ning Han Wentao Yao Kuochang Yin Nan Yin |
| author_facet | Guodong Xu Xiaoli Dong Yingying Tian Liang Ma Ning Han Wentao Yao Kuochang Yin Nan Yin |
| author_sort | Guodong Xu |
| collection | DOAJ |
| description | Abstract Objective The safety and efficacy of drug-eluting balloon on the treatment of intracranial atherosclerotic stenosis (ICAS) remain unclear. Here, we present our observation in a cohort study on the safety and efficacy of rapamycin-eluting balloon for patients with ICAS. Methods A total of 80 ICAS patients with stenosis degree of 70–99% were included. All patients were treated with rapamycin-eluting balloon and were followed up for 12 months after operation. Results All patients were successfully treated, where the mean stenosis severity reduced from 85.1 ± 7.6 to 6 ± 4.9%. 8 patients experienced immediate post-operational complications. Two patients passed away during the first month of the follow-up period. Recurrent ischemic syndrome and angiographic restenosis only appeared 7 days after operation. During later follow-up period, none of the patients had clinical angiographic restenosis or needed target vessel revascularization. Conclusion Our data suggest that intracranial stenting with rapamycin-eluting balloon seems to be safe and effective, although more clinical data are needed to support this notion. |
| first_indexed | 2024-04-09T15:06:49Z |
| format | Article |
| id | doaj.art-d3be3ab459964e2a87f925e49fe99a4c |
| institution | Directory Open Access Journal |
| issn | 1749-8090 |
| language | English |
| last_indexed | 2024-04-09T15:06:49Z |
| publishDate | 2023-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj.art-d3be3ab459964e2a87f925e49fe99a4c2023-04-30T11:27:38ZengBMCJournal of Cardiothoracic Surgery1749-80902023-04-011811510.1186/s13019-023-02204-6Evaluation of safety and efficacy of rapamycin-eluting balloon in patients with intracranial atherosclerotic stenosis: a cohort studyGuodong Xu0Xiaoli Dong1Yingying Tian2Liang Ma3Ning Han4Wentao Yao5Kuochang Yin6Nan Yin7Department of Neurology, Hebei General HospitalDepartment of Neurology, Hebei General HospitalDepartment of Neurology, Hebei General HospitalDepartment of Neurology, Hebei General HospitalDepartment of Neurology, Hebei General HospitalDepartment of Neurology, Hebei General HospitalDepartment of Neurology, Hebei General HospitalDepartment of Neurology, Hebei General HospitalAbstract Objective The safety and efficacy of drug-eluting balloon on the treatment of intracranial atherosclerotic stenosis (ICAS) remain unclear. Here, we present our observation in a cohort study on the safety and efficacy of rapamycin-eluting balloon for patients with ICAS. Methods A total of 80 ICAS patients with stenosis degree of 70–99% were included. All patients were treated with rapamycin-eluting balloon and were followed up for 12 months after operation. Results All patients were successfully treated, where the mean stenosis severity reduced from 85.1 ± 7.6 to 6 ± 4.9%. 8 patients experienced immediate post-operational complications. Two patients passed away during the first month of the follow-up period. Recurrent ischemic syndrome and angiographic restenosis only appeared 7 days after operation. During later follow-up period, none of the patients had clinical angiographic restenosis or needed target vessel revascularization. Conclusion Our data suggest that intracranial stenting with rapamycin-eluting balloon seems to be safe and effective, although more clinical data are needed to support this notion.https://doi.org/10.1186/s13019-023-02204-6Rapamycin-eluting balloonStenosisStrokeAngiography |
| spellingShingle | Guodong Xu Xiaoli Dong Yingying Tian Liang Ma Ning Han Wentao Yao Kuochang Yin Nan Yin Evaluation of safety and efficacy of rapamycin-eluting balloon in patients with intracranial atherosclerotic stenosis: a cohort study Journal of Cardiothoracic Surgery Rapamycin-eluting balloon Stenosis Stroke Angiography |
| title | Evaluation of safety and efficacy of rapamycin-eluting balloon in patients with intracranial atherosclerotic stenosis: a cohort study |
| title_full | Evaluation of safety and efficacy of rapamycin-eluting balloon in patients with intracranial atherosclerotic stenosis: a cohort study |
| title_fullStr | Evaluation of safety and efficacy of rapamycin-eluting balloon in patients with intracranial atherosclerotic stenosis: a cohort study |
| title_full_unstemmed | Evaluation of safety and efficacy of rapamycin-eluting balloon in patients with intracranial atherosclerotic stenosis: a cohort study |
| title_short | Evaluation of safety and efficacy of rapamycin-eluting balloon in patients with intracranial atherosclerotic stenosis: a cohort study |
| title_sort | evaluation of safety and efficacy of rapamycin eluting balloon in patients with intracranial atherosclerotic stenosis a cohort study |
| topic | Rapamycin-eluting balloon Stenosis Stroke Angiography |
| url | https://doi.org/10.1186/s13019-023-02204-6 |
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